Periodontal diseases, including gingivitis and periodontitis, are the most commonly occurring, yet very specific, infections of the oral cavity. When the infection is progressive, it changes from a reversible diagnosis of gingivitis to a less favorable, more difficult to reverse condition: periodontitis. Previously, research was focused on the microbiological aspects of the periodontitis. Curre...

The purpose of this article is to review available literature on proteomics in healthy and diseased periodontal structures. The proteins are the building blocks for both microorganisms and periodontium. Periodontitis is the result of complex interrelationship between infectious agents and host factors. The onset, progression and severity of periodontal disease are mainly mediated by various pro...

I n 2005, the American Academy of Periodontology undertook the development of guidelines for the management of patients with periodontitis. The development process took into consideration the latest research in the field of periodontics, comments from Academy members, and input from other dental organizations. The final product – Guidelines for the Management of Patients With Periodontal Diseas...

Atherosclerosis is the most common cause of myocardial infarction and ischemic stroke. Various risk factors have been identified for atherosclerosis. Recently, bacterial and viral organisms, which are involved in chronic inflammatory processes, have been also implicated in atherosclerosis development. Individuals with a prior history of periodontal diseases and/or tooth loss are considered to be...

I n 2005, the American Academy of Periodontology undertook the development of guidelines for the management of patients with periodontitis. The development process took into consideration the latest research in the field of periodontics, comments from Academy members, and input from other dental organizations. The final product – Guidelines for the Management of Patients With Periodontal Diseas...

PURPOSE OF REVIEW Periodontal diseases are inflammatory conditions that were once thought to have manifestations localized to the oral cavity alone, and were therefore considered the concern of only dentists and other oral health professionals. Emerging evidence has changed this view and now suggests that periodontal diseases may play a role in numerous conditions that impact systemic well bein...

Recent decades have brought significant progress in understanding the role of cytokines in many aspects of the development of periodontal disease associated with systemic disorders and increased risk of oral cancer. A thorough search of articles was carried out on the databases PubMed on the association of periodontal disease and obstetric pathologies, systemic diseases and cancer. Refs cited a...

Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by nonsurgical mechanical debridement and regular periodontal maintenance care. Periodontal surgery...

Periodontal diseases are multifactorial in nature. While microbial and other environmental factors are believed to initiate and modulate periodontal disease progression, there now exist strong supporting data that genetic polymorphis ms play a role in the predisposition to and progression of periodontal diseases. Variat ions in any number or combination of genes that control the development of ...

Periodontal diseases are characterized by pathological destruction of extracellular matrix (ECM) of periodontal tissues. Matrix metalloproteinases (MMPs) are a significant part of the degradation of ECM. However, the regulation of MMPs expression level in periodontal diseases is as yet undetermined. RECK (reversion-inducing cysteine-rich protein with Kazal motifs), a novel membrane-anchored inh...