Continuous environmental stimulation induced by exposure to enriched environment (EE) has yielded cognitive benefits in different models of brain injury. Perinatal asphyxia results from a lack of oxygen supply to the fetus and is associated with long-lasting neurological deficits. However, the effects of EE in middle-aged rats suffering perinatal asphyxia are unknown. Therefore, the aim of the ...

OBJECTIVE To determine risk factors for perinatal asphyxia. DESIGN Cohort study. SETTING Teaching hospital. METHODS All consecutive hospital births were evaluated during the study period. Asphyxia was defined on intrapartum and neonatal resuscitation criteria. Maternal, intrapartum and neonatal variables were recorded in all births. Data was analyzed after stratifying for live and stillbi...

The process of birth (parturition) has a critical impact on normal human development. Any deviations from the typical parturition process are defined clinically as birth complications, and have been linked to the development of neurological deficits. Two relatively common types of consequences from birth complications are perinatal asphyxia and Caesarean Section delivery (C-section); however, C...

BACKGROUND Asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. The present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (NRBC) cells, for early diagnosis of perinatal asphyxia. OBJECTIVE In this study, we evaluated the mean NR...

Perinatal asphyxia is defined as an oxygen deprivation that occurs around the time of birth, and may be caused by several perinatal events. This medical condition affects some four million neonates worldwide per year, causing the death of one million subjects. In most cases, infants successfully recover from hypoxia episodes; however, some patients may develop HIE, leading to permanent neurolog...

Background Fetal growth restriction is the second leading cause of perinatal morbidity and mortality. The incidence of intrauterine growth restriction (IUGR) is estimated to be approximately 5 percent in the general obstetric population. Abnormal uterine artery suggest a maternal cause for the growth restriction where as normal uterine artery Doppler studies suggest that a fetal cause. Use of u...

A total of 440 perinatal deaths occurring in a maternity hospital over a 6 year period have been analysed clinically and pathologically. The decline in mortality could be attributed to a reduction in asphyxial deaths, lethal malformations, and macerated stillbirths. The establishment of a neonatal intensive care unit seemed to have been more successful in combating birth asphyxia than respirato...

Background: Among neonates, lack of oxygen results in multi-organ failure especially causing brain hypoxia resulting hypoxic-ischemic encephalopathy (HIE). Aim: To determine diagnostic accuracy LDH detecting birth asphyxia keeping clinical signs HIE as gold standard. Study Design: Cross-sectional study. Methodology: Neonates (n=180) fulfilling inclusion criteria were enrolled this study from th...

The fetal environment and circulatory patterns are very different from that of extrauterine life. fetus evolved to thrive grow in a relative hypoxemic adapted several mechanisms response changes oxygen concentration the blood ensure optimal delivery brain heart. However according estimates World Health Organization world 4 9 million newborns born annually state perinatal asphyxia. In economical...