Perianal mucinous adenocarcinoma is a rare tumor which may be associated with long-standing chronic perianal sepsis. Early diagnosis is challenging and is based on a high index of clinical suspicion and specific histological features. Definitive treatment is surgical, in the form of an abdomino-perineal resection. We hereby describe a case of a perianal mucinous adenocarcinoma arising from long...

OBJECTIVE To describe the clinicopathological spectrum of Lymphangioma Circumscriptum (LC). STUDY DESIGN Observational case series. PLACE AND DURATION OF STUDY Department of Pathology and Microbiology, AKUH, Karachi, from 2002 to 2012. METHODOLOGY All reported cases of LC were retrieved from medical record. Clinical and pathological features were noted. Frequency percentages were determin...

Extramammary Paget’s disease is an uncommon cutaneous adenocarcinoma, characterized by glandular differentiation and an insidious course. The condition may or may not be associated with an underlying adnexal or visceral malignancy. Because of its rarity, the pathogenesis is unclear, and standardization of treatment is lacking. The diagnosis is made histopathologically, and management is based o...

INTRODUCTION Scalloping sacral arachnoid cyst though a rare condition, should be suspected in cases of persistent perianal pain without any obvious urological or anorectal pathology. Such difficult cases justify ordering an M.R.I of spine as plain X-Rays and clinical examination may come out to be inconclusive. X-ray in later stages may show changes corresponding to scalloping of bone due press...

UNLABELLED Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor (BLT) is a very rare sexually transmitted disease that affects the ano-genital region. BLT is a slow growing cauliflower-like tumor, but unlike simple condyloma, it is locally aggressive and destructive, malignant transformation occuring in 40-60% of cases. We present a case of perianal carcinomatous BLT and discuss s...

Transanal endoscopic microsurgery (TEM) is a minimally invasive technique for local excision of benign and malignant neoplasms in the rectum. Indications for this technique are constantly changing and extending. The aim of this study is to describe a case of a unique and innovative application of this surgical technique. A 72-year-old patient was admitted to the Clinical Department of General a...

Perianal region is an uncommon site for Rhabdomyosarcoma. Early diagnosis is essential in these cases, as 25% of patients present with metastasis at the time of diagnosis. FNAC is simple and useful procedure for making an early diagnosis and helping clinicians for prompt intervention. Previously, a single case had been reported of rhabdomyosarcoma occuring 2 years after a surgery for hamartoma ...

Perianal skin lesions, such as skin tags, can be an early presenting sign of Crohn's disease. Surgical intervention on these lesions may increase the risk of fistula development and lead to worse outcomes. This case series examined 8 patients who underwent surgical intervention on what appeared to be benign perianal skin lesions, only to reveal fistulas leading to the diagnosis of Crohn's disea...

BACKGROUND Perianal fistulizing Crohn's disease is one of the most severe phenotypes of inflammatory bowel diseases. Combined therapy with seton placement and anti-TNF therapy is the most common strategy for this condition. OBJECTIVES The aim of this study was to analyze the rates of complete perianal remission after combined therapy for perianal fistulizing Crohn's disease. METHODS This wa...