INTRODUCTION Appendicitis is the most common emergency condition in children. Historically, a 3-drug regimen consisting of ampicillin, gentamicin, and clindamycin (AGC) has been used postoperatively for perforated appendicitis. A retrospective review at our institution has found single day dosing of ceftriaxone and metronidazole (CM) to be a more simple and cost-effective antibiotic strategy. T...

BACKGROUND For more than a century, appendicectomy has been the treatment of choice for appendicitis. Recent trials have challenged this view. This study assessed the benefits and harms of antibiotic therapy compared with appendicectomy in patients with non-perforated appendicitis. METHODS A comprehensive search was conducted for randomized trials comparing antibiotic therapy with appendicect...

IMPORTANCE Pediatric appendicitis outcomes have been shown to be influenced by several patient-, surgeon-, and hospital-level factors. However, to our knowledge, no prior studies have investigated the effect of health care systems on outcomes. OBJECTIVE To test the hypothesis that the outcomes of children with appendicitis are better in the Canadian single-payer universal health care system t...

BACKGROUND Acute appendicitis (AA) is a common surgical problem that is associated with an acute-phase reaction. Previous studies have shown that cytokines and acute-phase proteins are activated and may serve as indicators for the severity of appendicitis. The aim of this study was to compare diagnostic value of different serum inflammatory markers in detection of phlegmonous or perforated appe...

OBJECTIVE Over 9.6 million ED visits occur annually for abdominal pain in the US, but little is known about the medical outcomes of these patients based on demographics. We aimed to identify disparities in outcomes among children presenting to the ED with abdominal pain linked to race and SES. METHODS Data from 4.2 million pediatric encounters of abdominal pain were analyzed from 43 tertiary ...

Introduction The incidence of acute appendicitis in pregnancy is 1:2000 (1:700 ÷ 3000); 60% suffer from acute appendicitis in the first half of pregnancy. When perforated appendicitis complicated by diffuse peritonitis, maternal mortality rate reaches 16.7%, with perinatal loss in the 19,4-50%. Explainable limitation application of instrumental diagnostic methods at different stages of pregnanc...

OBJECTIVE Acute appendicitis is one of the most common acute surgical pathology we encountered. In this study we investigated our pregnant cases of appendicitis, and reviewed literature. METHODS A total of 21 pregnant women who underwent appendectomy with the initial diagnosis of acute appendicitis in Istanbul Medeniyet University Clinics of General Surgery between January 2012, and December ...

Introduction. Intestinal perforation is a known complication after colonoscopy. However, appendiceal involvement with inflammation and perforation is extremely rare and only 37 cases of postcolonoscopy appendicitis have been reported so far. We describe a case of perforated appendicitis 24 hours after colonoscopy that was treated successfully in our Department. Case Report. A 60-year-old female...

INTRODUCTION Acute appendicitis is one of the most common surgical diseases, but perforated appendicitis resulting in necrotizing fasciitis of the abdominal wall is exceedingly rare. PRESENTATION OF CASE A 71-year-old male presented to the emergency department with one week of severe right-sided abdominal pain. He was hypothermic, hypotensive, and tachycardic. His abdomen was distended, with ...