Eruptive phenomena at all scales, from hydrothermal geysers to flood basalts, can potentially be initiated or modulated by external mechanical perturbations. We present evidence for the triggering of magmatism on a global scale by the Chicxulub meteorite impact at the Cretaceous-Paleogene (K-Pg) boundary, recorded by transiently increased crustal production at mid-ocean ridges. Concentrated pos...

................................................................................................. pg. iii Acknowledgements ...................................................................................... pg. v Introduction ............................................................................................... pg. vi 1Moving into the Middle Ground between Compatibilism and Incompat...

The recently-finished Edinburgh UVX quasar survey at B < 18 is used together with other complete samples to estimate the shape and evolution of the optical luminosity function in the redshift range 0.3 < z < 2.2. There is a significantly higher space density of quasars at high luminosity and low redshift than previously found in the PG sample of Schmidt & Green (1983), with the result that the ...

Recently, convincing evidence was found for extremely large X-ray absorption by column densities > 1023 cm−2 in broad absorption line quasars. One consequence of this is that any soft X-ray emission from these QSOs would be the scattered light or leaked light from partially covering absorbing material. A detection of the unabsorbed soft X-ray and absorbed hard X-ray component will allow to dete...

We prove a big monodromy result for a smooth family of complex algebraic surfaces of general type, with invariants pg = q = 1 and K 2 = 3, that has been introduced by Catanese and Ciliberto. This is accomplished via a careful study of degenerations. As corollaries, when a surface in this family is defined over a finitely generated extension of Q, we verify the semisimplicity and Tate conjecture...

The Meaning in Isolation Thesis features prominently in Russell’s writings on definite descriptions.1 In those writings Russell sets out to defend the view that definite descriptions “never have any meaning in themselves.” (Russell, 1905, pg. 42) He proceeds to say that a definite description “is essentially part of a sentence, and does not, like most single words, have any significance on its ...

In order to determine the therapeutic value of penicillins in the management of anaerobic infections caused by Bacteroides fragilis, the antibacterial activity of penicillin G, ampicillin, and carbenicillin against 10 strains of B. fragilis subsp. fragilis, isolated from clinical material, was studied. This was undertaken by using a triple-layer technique, enzymatic inactivation of the antibiot...

Penicillin G acylase (PGA) is a heterodimeric enzyme synthesized as a single-polypeptide precursor that undergoes an autocatalytic processing to remove an internal spacer peptide to produce the active enzyme. We constructed a single-chain PGA not dependent on autoproteolytic processing. The mature sequence of the beta-domain was expressed as the N terminus of a new polypeptide, connected by a r...

During investigations into the production of 13-lactamase inhibitory activity by microorganisms we studied the culture Streptomyces gedanensis ATCC 4880. This culture has been reported by HATA et al.' to produce (3-lactamase inhibitory activity, the active component designated KA107 was shown to be a high molecular weight substance, probably a protein. Our studies have shown that S. gedanensis ...

A large volume of data on variations in serum penicillin levels has been obtained from work carried out with depot preparations of procaine benzyl penicillin in oil (to be published). Figure 1 shows frequency histograms of blood levels obtained in humans 24 hours after a single fixed dose of the same preparation. Large groups of individuals were involved and there was an interesting difference ...