Multifunctional nanocomposites that have multiple therapeutic functions together with real-time imaging capabilities have attracted intensive concerns in the diagnosis and treatment of cancer. This study developed epidermal growth factor receptor (EGFR) antibody-directed polydopamine-coated Fe3O4 nanoparticles (Fe3O4@PDA NPs) for magnetic resonance imaging and antitumor chemo-photothermal thera...

BACKGROUND Peptide receptor radionuclide therapy (PRRT), employed for treatment of neuroendocrine tumors (NETs) is based on over-expression of Somatostatin Receptors (SSTRs) on NETs. It is, however, limited by high uptake and retention of radiolabeled peptide in kidneys resulting in unnecessary radiation exposure thus causing nephrotoxicity. Employing a nanocarrier to deliver PRRT drugs specifi...

Two forms of pollutants are usually discharged from scouring wool fleece; namely the effluent liquid phase and solid phase. These phases comprise a significant quantity wax which would be suitable candidate for valuable products applications. This work is devoted to extraction, recovery, characterization lanolin fleece different sheep breeds assign possible ways its utilization in textile field...

hematogenous metastasis of tumor. Recently, various antiangiogenic therapeutic modalities have accomplished remarkable progress. We previously proposed cancer antineovascular therapy (ANET): Indirect tumor regression is achieved through damaging neovessel endothelial cells by anticancer drugs, since neovessel endothelial cells are growing cells and are susceptible to anticancer drugs like as tu...

A protein-resistant surface has been constructed on the poly(methyl methacrylate) (PMMA) microfluidic chips based on a one-step modification. The copolymer of butyl methacrylate (BMA) and poly(ethylene glycol) methyl ether methacrylate (PEGMA) is synthesized to introduce a dense PEG molecular brush-like coating on the PMMA microchannel surfaces via the anchoring effect of the hydrophobic BMA un...

This study is to prepare the pantoprazole sodium enteric-coated tablet which is compacted by pellets. The enteric-coated pantoprazole sodium pellets were prepared by fluid bed coating technology. The pantoprazole sodium enteric-coated tablets were prepared by direct compression of the enteric-coated pellets and suitable excipients. In vitro dissolution method and scanning electron microscope me...

Magnetic nanoparticles (MNPs) are widely used materials for biomedical applications owing to their intriguing chemical, biological and magnetic properties. The evolution of MNP based (such as hyperthermia treatment drug delivery) could be advanced using nanofluids (MNFs) designed with a biocompatible surface coating strategy. This study presents the first report on loading/release capability MN...