We describe a 19 year old woman with systemic lupus erythematosus on corticosteroid therapy, who developed bilateral, multiple, gas-forming Salmonella enteritidis leg abscesses and osteomyelitis mimicking deep vein thrombosis. The infection was treated successfully by a combination of surgical drainage and intravenous ceftriaxone, followed by prolonged oral pefloxacin. This rare case of gas-pro...

The aim of this study was to determine the antibacterial activity some antibiotic and disinfectant against airborne bacteria from restaurants. Airborne were isolated five different restaurants using open plate method characterized standard microbiological techniques. susceptibility isolates antibiotics disinfectants determined Kirby-Bauer disc diffusion well diffusion. predominant identified in...

Isolate was characterized by biochemical and serological tests. Slide agglutination with typing antisera (Central Research Institute, Kasauli) produced a profile of O: 2,H: a. The isolate was sensitive to ampicillin, ampicillin-sulbactam, amoxicillin-clavulanic acid , tetracycline, chloramphenicol, gentamicin, ofloxacin, amikacin, erythromycin, ciprofloxacin, pefloxacin, and gatifloxacin. The p...

Effective therapy of infections caused by facultative intracellular micro-organisms, which persist after ingestion by mononuclear phagocytic cells, requires antibiotics which inactivate these intraphagocytic bacteria. A previous study demonstrated that intracellular concentrations of normethylpefloxacin, Ci, were the result of simple diffusion and an active efflux involving organic anion transp...

Fluoroquinolones are new generations of antibiotics and are increasingly used in human and veterinary medicine. We tested isolates of 63 and 50 isolates of Klebsiella pneuminiae from cattle and swine respectively from different locations in Ado Ekiti, Nigeria for the susceptibility to fluoroquinolones. Using the agar disk diffusion test, susceptibilities to the following fluoroquinolones were t...

Antibiotic susceptibility testing of two isolates of the Q-fever agent, Coxiella burnetii, was performed with recently and persistently infected L929 fibroblast cells. The two genetically distinct isolates, Nine Mile and Priscilla, are implicated in two different clinical disease syndromes, acute and chronic Q fever, respectively. We compared the efficacies of rifampin, doxycycline, and five 4-...