Familial Mediterranean fever (FMF) has been associated with hematological malignancies but has not been reported in association with Hodgkin lymphoma (HL). We hereby describe the first pediatric patient with FMF and stage IIA nodular sclerosis HL. She was treated with prednisone, doxorubicin, vincristine and etoposide (OEPA) being on therapy with colchicine. However, she suffered more than expe...

Metastatic skin cancer is a rare complication of internal malignancies.  Patients who develop cutaneous metastases rarely present with a zosteriform distribution.  Herein, we describe a 65-year-old woman with a prior history of breast cancer in whom zosteriform metastases developed along her left T8-9 abdominal dermatomes.

The Hypertension is divided into two types: primary and secondary. the secondary type, is particularly due to renal and arterial origin and is mostly seen. In children the Secondary hypertension caused by malignancies is rare. This is a case of abdominal rhabdomyosarcoma with malignant hypertension.

OBJECTIVE To summarize rates of abdominal pain in pediatric inflammatory bowel disease, and to examine associations of abdominal pain, disease activity, and health-related quality of life (HRQoL). METHODS 44 youths aged 11-18 years completed ratings of abdominal pain, whereas youths and mothers provided ratings of HRQoL at Time 1 (T1) and Time 2 (T2; 6 months later). Disease activity was rate...

BACKGROUND Tumor genesis of many pediatric malignancies remains unclear. Data of immune function are lacking at diagnosis. We prospectively analyzed 109 pediatric patients with malignancy at diagnosis. METHODS Lymphocyte subpopulations were characterized by FACS, TREC-assay, and Immunoscope, cytokines by FACS and ELISA. OBSERVATIONS We detected higher values of CD4(+) T cells and consecutiv...

The overall prognosis for most pediatric cancers is good. Mortality for all childhood cancers combined is approximately half what it was in 1975, and the survival rates of many malignancies continue to improve. However, the incidence of childhood cancer is significant and the related emergencies that develop acutely carry significant morbidity and mortality. Emergency providers who can identify...

Pediatric sarcomas are rare malignancies accounting for about 10% of solid tumors in childhood. Sarcomas represent a heterogeneous group malignancies, especially they include Rhabdomyosarcoma (RMS) and Non-Rhabdomyosarcoma Type (STSNR). Therapeutic management pediatric is challenging. Multidisciplinary approach including chemotherapy, surgery radiotherapy the treatment choice. The correct affec...

Background: Children with blunt abdominal trauma (BAT) can be risk stratified for intra-abdominal injury (IAI) through a combination of readily accessible clinical variables. The aim of this study was to identify ultrasound and laboratory studies that accurately identify IAI while limiting unnecessary CT-scan among children without injury. Materials and Methods We conducted a prospective, obse...

Abdominal wall blocks are an effective regional anesthetic technique to provide sufficient analgesia in abdominal surgery. This article reviews the use of abdominal wall blocks in pediatric regional anesthesia.