This paper defines a multiobjective variant of the Pickup and Delivery Problem (PDP), called PDP with Time Windows and Demands (PDP-TW-D), and approaches the problem with a novel memetic optimization algorithm. With respect to multiple optimization objectives, the goal of PDP-TW-D is to find a set of Pareto-optimal routes for a fleet of vehicles in order to serve given transportation requests. ...

Spend your few moment to read a book even only few pages. Reading book is not obligation and force for everybody. When you don't want to read, you can get punishment from the publisher. Read a book becomes a choice of your different characteristics. Many people with reading habit will always be enjoyable to read, or on the contrary. For some reasons, this assembly language programming for pdp 1...

Vascular injury after balloon angioplasty results in the rapid activation of platelets leading to the release of growth factors and vasoactive substances. In addition, up-regulation of tissue factor (TF) and an increased production of reactive oxygen species (ROS) have been detected at sites of vascular injury. We investigated whether platelet-derived products (PDP) released from activated huma...

This paper introduces a special issue of Cognitive Science initiated on the 25th anniversary of the publication of Parallel Distributed Processing (PDP), a two-volume work that introduced the use of neural network models as vehicles for understanding cognition. The collection surveys the core commitments of the PDP framework, the key issues the framework has addressed, and the debates the frame...

Network virtualization provides the ability to run multiple concurrent virtual networks over a shared substrate. However, it is challenging to design such a platform to host multiple heterogenous and often highly customized virtual networks. Not only high degree of flexibility is desired for virtual networks to customize their functions, fast packet forwarding is also required. This paper prese...

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1 receptor tyrosine kinase), AGE-1 (PI 3-kinase), and additional downstream serine/threonine kinases that ultimately phosphorylate and negatively regulate the single FOXO transcription factor homolog DAF-16. Phospha...

This paper presents the extraction of a legal access control policy and a conflict resolution policy from the EU Data Protection Directive [1]. These policies are installed in a multi-policy authorization infrastructure described in [2, 3]. A Legal Policy Decision Point (PDP) is constructed with a legal access control policy to provide automated decisions based on the relevant legal provisions....

BACKGROUND Symptomatology and physiology differ between men and women and across the menstrual cycle in irritable bowel syndrome (IBS). Ovarian hormones influence 5-hydroxytryptamine (5-HT), an amine known to play a role in gut motor-sensory function. AIM To assess the effects of gender and menstrual status on platelet-depleted plasma (PDP) 5-HT concentration in IBS patients with diarrhoea (I...

The pick-up and delivery problem (PDP) consists in finding a set of optimal routes for a fleet of vehicles respecting the precedence and pairing constraints and visiting all transportation requests. The transport of personnel on oil platforms is a real application of PDP which we are interested in. The problem is modeled as a set covering problem that is solved via a column generation technique...

The PDP(Partial Dominant Pruning) method is known as most practical method to reduce overlapped broadcasting messages by designating forward node as in-fly type when broadcasting occurs in the mobile wireless network with directional antenna. In this paper, we introduce DPDP(Directional PDP) that reduces not only number of nodes but number of used antenna elements simultaneously. By simulation,...