TAS-103, a new anticancer drug, induces DNA cleavage by inhibiting the activities of topoisomerases I and II. We investigated the mechanism of TAS-103-induced apoptosis in human cell lines. Pulsed field gel electrophoresis revealed that in the leukemia cell line HL-60 and the H(2)O(2)-resistant subclone, HP100, TAS-103 induced DNA cleavage to form 1-2-Mb fragments at 1 h to a similar extent, in...

OBJECTIVE Type 1 diabetes is associated with a high risk of coronary heart disease (CHD), despite the absence of dyslipidemia. Oxidative modification may render LDLs more atherogenic. We aimed to assess antioxidant status in type 1 diabetes and its association with coronary artery calcification (CAC). RESEARCH DESIGN AND METHODS Total antioxidant status (TAS) of serum was measured using the T...

Teaching Assistants (TAs) play an important role in supporting research-based instructional environments, yet the connection between TAs' pedagogical beliefs and instructional practices is not well understood. We build upon a broad foundation of research on the nature of pedagogical content knowledge to develop an analytic framework for characterizing how physics TAs both describe and enact the...

In this correspondence we presents the performance analysis of multiple-input multiple-output (MIMO) technique incorporating maximal-ratio combining with transmit antenna selection (MRC/TAS) in frequency-flat Rayleigh fading channels. The expression of probability density function (pdf) for MRC/TAS (Nt , 1; Nr) scheme has been derived. The probability of outage is examined first. Further by the...

IJSER © 2017 http://www.ijser.org Abstract—In this paper, we analyze the combined performance of joint transmit and receive antenna selection (JTRAS), transmit antenna selection/maximum ratio combining (TAS/MRC) and transmit antenna selection/receiver antenna selection (TAS/RAS) approach in the context of physical layer security (PLS) in multiple-input multiple-output (MIMO) wiretap channels. W...

Total antioxidant status (TAS), and the influence of treatment and correlation between TAS and parameters involved in metabolic syndrome (MS) in pediatric cancer survivors were evaluated. One hundred children and adolescents were studied. Twenty-five survivors received radiotherapy, 12 were obese or overweight.Additionally, we analyzed TAS in eight children with acute lymphoblastic leukemia (AL...

UNLABELLED Low health literacy and alexithymia have separately been emphasized as barriers to patient-practitioner communication, but the association between the two concepts has not been explored. OBJECTIVE To test the hypothesis that low oral health literacy and alexithymia are associated. METHOD Adults (n=127) aged 21-80 years (56% women) participated in this cross-sectional study. Oral ...

CONTEXT Therapy assistants (TAs) are widely used in the delivery of therapy services in rural Western Australia (WA). Appropriate training for TAs is an essential part of their practice; however, to date most TAs are trained 'on-the-job', thus taxing the scarce resources of rural and remote allied health professionals (AHPs). There has been limited recognized training that is suitable to their ...

Results: TOS levels and OSI values were signifi cantly higher in nonsurvivors compared with those in survivors. However, there was no signifi cant diff erence in TAS levels between survivors and nonsurvivors. GCS and RTS showed negative correlations with TOS levels, but neither was signifi cantly related to OSI levels. Furthermore, GCS scores were negatively correlated with TAS levels, whereas ...