Following the recent publication of the PRAMI trial, the appearance of the article entitled ‘‘Multivessel approach in ST-elevation myocardial infarction: Impact on in-hospital morbidity and mortality’’ by Santos et al. in this issue of the Journal could not be more timely. The study analyzed a population of patients with ST-elevation myocardial infarction (STEMI) included in the Portuguese Regi...

BACKGROUND Guidelines advise testing for ischemia, such as with stress testing, before elective percutaneous coronary intervention (PCI). However, pre-PCI stress testing is not always done; the implications of this practice are not known. Our objective was to evaluate whether receipt of stress testing before elective PCI predicts mortality. METHODS AND RESULTS Using claims data from a 20% ran...

Aims Optical frequency domain imaging (OFDI) is a recently developed, light-based, high-resolution intravascular imaging technique. Intravascular ultrasound (IVUS) is a widely used, conventional imaging technique for guiding percutaneous coronary intervention (PCI). We aimed to demonstrate the non-inferiority of OFDI-guided PCI compared with IVUS-guided PCI in terms of clinical outcomes. Meth...

BACKGROUND With the reduction in restenosis rates by drug-eluting stents, there is new controversy concerning the optimal management of incidental, nontarget lesions identified during percutaneous coronary intervention (PCI). Such lesions have been treated conservatively because of risk of restenosis but now are being considered for PCI to prevent plaque instability. However, the impact of inci...

Protein C inhibitor (PCI), which was originally identified as an inhibitor of activated protein C, also efficiently inhibits coagulation factors such as factor Xa and thrombin. Recently it was found, using purified proteins, that the anticoagulant thrombin-thrombomodulin complex was also inhibited by PCI. The paradoxical inhibitory effect of PCI on both coagulant and anticoagulant proteases rai...

chronic total occlusion (cto) intervention is still a challenging problem. the aim of this study is to determine factors that affect pci results.the study was conducted on 72 patients in two centers. cto angioplasty was done by the antegrade approach from the femoral and/or radial approach. the role of age, gender, anatomical variations such as calcification, length of the lesion, proximal bend...

the existence of ra 226 is proved and measured by radiom emanation-method in waters and food products of north , north west and north – east of iran. a total of 126 water, 249 food and 22 air samples have been examined. the concertration of ra 226 in waters found to be 0.01 to 1.104 pci/1 and in food products from 0.01 to pci/gr. ash.the amount found in due ranges from 0.003 to 0.227 pci/m 3.it...

OBJECTIVES This prespecified subgroup analysis examined the effect of diabetes on left main coronary disease (LM) and/or three-vessel disease (3VD) in patients treated with percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in the SYNTAX trial. METHODS Patients (n = 1800) with LM and/or 3VD were randomized to receive either PCI with TAXUS Express paclitaxel-elu...

BACKGROUND Psychosocial stress and activation of neutrophil granulocytes are increasingly recognized as major risk factors of coronary artery disease (CAD), but the possible relationship of these two factors in CAD patients is largely unexplored. Activation of neutrophils was reported to be associated with stenting; however, the issue of neutrophil state in connection with percutaneous coronary...