Normal development of the mouse embryo requires the presence of both paternal and maternal genomes. This is due to functional differences having their origin in a differential imprinting of parental genomes. Furthermore, several lines of evidence show that the very early interactions between egg cytoplasm and pronuclei may influence the programming of the embryonic genome and modulate the funct...

Objective: Early year experiences with parents play an important role in the development of personality of individuals. In this regard, the present study aimed at assessing the relationship between parental bonding and type and severity of psychopathology in young adults.  Methods: A total of 361 students (205 boys and 156 girls) of Tabriz University were selected by cluster sampling me...

A male factor is implicated in more than 50% of couples treated with IVF. However, neither the routine testing of male fertility potential nor its treatment address the specific mechanisms by which spermatozoal factors may impact upon reproductive outcome. An important function of spermatozoa is to deliver the paternal genome to the oocyte. Recently, a number of acquired spermatozoal nuclear fa...

Crouzon syndrome and Pfeiffer syndrome are both autosomal dominant craniosynostotic disorders that can be caused by mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. To determine the parental origin of these FGFR2 mutations, the amplification refractory mutation system (ARMS) was used. ARMS PCR primers were developed to recognize polymorphisms that could distinguish maternal an...

The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise fish (P and S) in predator exploration and avoidance, using predator models. We...

Population divergence in antipredator defence and behaviour occurs rapidly and repeatedly. Genetic differences, phenotypic plasticity or parental effects may all contribute to divergence, but the relative importance of each of these mechanisms remains unknown. We exposed juveniles to parents and predators to measure how induced changes contribute to shoaling behaviour differences between two th...

In the mouse the insulin-like growth factor receptor type 2 gene (Igf2r) is imprinted and maternally expressed. Igf2r encodes a trans-membrane receptor that transports mannose-6-phosphate tagged proteins and insulin-like growth factor 2 to lysosomes. During development the receptor reduces the amount of insulin-like growth factors and thereby decreases embryonic growth. The dosage of the gene i...

is ortodox in females but highly specialised in males, showing elimination of the paternally derived genome (1st division), and the non-disjunction of the two X chromatids and elimination of one chromatid of each autosome during the 2nd division. When the zygotic nuclei reach the egg cortex, one paternal X chromosome is eliminated in the somatic cells of embryos destined to be females (2X;2A) a...

Background Recurrent spontaneous abortion (RSA) is a complication in pregnancy that results into fetus rejection by mother and several factors such as anatomical, genetic and immunological problems can be its etiologic causes. Paternal lymphocyte therapy as an immunotherapy for these patients has been more evaluated. The purpose of lymphocyte therapy is stimulation of the mother immune system t...

This study investigated the association between Iranian university students' perception of their fathers and their object-relation and defense mechanism. Participants were 438 students between 18-22 years from Allameh Tabatabae University, who agreed to fill the Fatherhood Scale out (Dick, 2004), Bell object relation inventory and defense mechanism style, and defense style questionnaire (DSQ-40...