Sina Ebrahimi, Alireza Ghoreifi, Behnam Shakiba, Arash Azaripour, Hamid Deldadeh, Amir Reza Elahian, Mazaher Hadi, Parvin Emadi, Hamed Rajaee, Mehdi Dehghani, Lily Nosraty. Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Urology Department, Mashhad University of Medical Sciences, Mashhad, Iran; Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, I...

SPECIAL FOCUS ON ADVANCES IN NETWORK AND SYSTEM SECURITY 382 Advances in Network and System Security: Editorial Statement Jiankun Hu, Yang Xiang and Wanlei Zhou 384 Secure-TWS: Authenticating Node to Multi-user Communication in Shared Sensor Networks Leonardo B. Oliveira, Aman Kansal, Conrado P.L. Gouvêa, Diego F. Aranha, Julio López, Bodhi Priyantha, Michel Goraczko and Feng Zhao 397 Dynamic S...

In this paper a new criterion for clusters validation is proposed. Many stability measures to validate a cluster have been proposed such as Normalized Mutual Information. We propose a new criterion for clusters validation. The drawback of the common approach is discussed in this paper and then a new asymmetric criterion is proposed to assess the association between a cluster and a partition whi...

Stable isotope labeling by amino acids in cell culture (SILAC) has become a versatile tool for quantitative, mass spectrometry (MS)-based proteomics. Here, we completely label mice with a diet containing either the natural or the (13)C(6)-substituted version of lysine. Mice were labeled over four generations with the heavy diet, and development, growth, and behavior were not affected. MS analys...

Dynamic interactions of cells with their environment regulate multiple aspects of tissue morphogenesis and function. Integrins are the major class of cell surface receptors that recognize and bind extracellular matrix proteins, resulting in the engagement and organization of the cytoskeleton as well as activation of signalling pathways to regulate cell behaviour and morphogenetic processes. The...

Nephrin, a structural molecule, is also a signaling molecule after phosphorylation. Inhibition of nephrin phosphorylation is correlated with podocyte injury. The PINCH-1-ILK-α-parvin (PIP) complex plays a crucial role in cell adhesion and cytoskeleton formation. We hypothesized that nephrin phosphorylation influenced cytoskeleton and cell adhesion in podocytes by regulating the PIP complex. The...

Cytoskeleton-mediated forces regulate the assembly and function of integrin adhesions; however, the underlying mechanisms remain unclear. The tripartite IPP complex, comprising ILK, Parvin, and PINCH, mediates the integrin-actin link at Drosophila embryo muscle attachment sites (MASs). Here, we demonstrate a developmentally earlier function for the IPP complex: to reinforce integrin-extracellul...