نتایج جستجو برای: paramyxovirus 1
تعداد نتایج: 2753530 فیلتر نتایج به سال:
Table. Conserved nucleotide sequences for the gene start, intergenic region, and gene stop of Mojiang paramyxovirus and henipaviruses* Variable Gene stop Intergenic region Gene start MojV, gene /N CTT AGGATTCAGG N/P TTAAACAAAA CTT AGGATCCAAG P/M TCATAAAAAA CTT AGGAGTCAAG M/F ATATAAAAAA CTT AGGTGTCAGG F/G TTAATAAAAA CTT AGGAGTCAGG G/L TTACAAAAAA CTT AGGATTCACG Consensus sequences for henipavirus...
Members within the paramyxovirus subfamily Paramyxovirinae constitute a large number of highly virulent human and animal pathogens. The glycoproteins present on these viruses are responsible for mediating host cell attachment and fusion and are key targets for the design of antiviral entry inhibitors. In the present review, we discuss recent structural studies which have led to a better underst...
Parainfluenza virus 5 (PIV5) is an enveloped, single-stranded, negative-sense RNA virus of the Paramyxoviridae family. PIV5 fusion and entry are mediated by the coordinated action of the receptor-binding protein, hemagglutinin-neuraminidase (HN), and the fusion protein (F). Upon triggering by HN, F undergoes an irreversible ATP- and pH-independent conformational change, going down an energy gra...
Enveloped viruses such as HIV and members of the paramyxovirus family use metastable, proteinaceous fusion machineries to merge the viral envelope with cellular membranes for infection. A hallmark of the fusogenic glycoproteins of these pathogens is refolding into a thermodynamically highly stable fusion core structure composed of six antiparallel α-helices, and this structure is considered ins...
Characterization of recent outbreaks of fatal encephalitis in southeast Asia identified the causative agent to be a previously unrecognized enveloped negative-strand RNA virus of the Paramyxoviridae family, Nipah virus. One feature linking Nipah virus to this family is a conserved cysteine-rich domain that is the hallmark of paramyxovirus V proteins. The V proteins of other paramyxovirus specie...
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