Assessing natural selection on a phenotypic trait in wild populations is of primary importance for evolutionary ecologists. To cope with the imperfect detection of individuals inherent to monitoring in the wild, we develop a nonparametric method for evaluating the form of natural selection on a quantitative trait using mark-recapture data. Our approach uses penalized splines to achieve flexibil...

conclusions in this study, sick sinus syndrome and pacemaker mode followed by syncope were independently associated with increased mortality. results survival data were available for 1030 (80%) patients (median age = 71 years [5th to 95th percentile range: 26 - 86 years]) and follow-up was completed for 84.28% of them. according to the results, 56% of the patients had received dual-chamber syst...

With the release of Stata 14 came the mestreg command to fit multilevel mixed effects parametric survival models, assuming normally distributed random effects, estimated with maximum likelihood utilising Gaussian quadrature. In this article, I present the user written stmixed command, which serves as both an alternative and a complimentary program for the fitting of multilevel parametric surviv...

flexsurv is an R package for fully-parametric modeling of survival data. Any parametric time-to-event distribution may be fitted if the user supplies a probability density or hazard function, and ideally also their cumulative versions. Standard survival distributions are built in, including the three and four-parameter generalized gamma and F distributions. Any parameter of any distribution can...

BACKGROUND Hemodialysis is the most common renal replacement therapy in patients with end stage renal disease (ESRD). OBJECTIVES The present study compared the performance of various parametric models in a survival analysis of hemodialysis patients. METHODS This study consisted of 270 hemodialysis patients who were referred to Imam Khomeini and Fatima Zahra hospitals between November 2007 a...