Bovine papilloma antigen detected by fluorescent antibody was correlated with the appearance of infectious virus and with epithelial hyperplasia and hyperkeratinization in the developing bovine cutaneous papilloma. Neither antigen nor infectious virus was found in the earliest stages of growth characterized by connective tissue pro liferation and by little or no epithelial change. The cellular ...

Background: There is a growing interest in development of an effective adjuvant system for improving DNA vaccines. Recent findings have confirmed an important role for autophagy in both innate and adaptive immunity. The current study was undertaken to determine the efficacy of autophagy induction with Beclin-1, as a novel adjuvant system, in mice immunized with human papilloma virus (HPV) DNA v...

BACKGROUND The development of molecular probes capable of recognizing virus-infected cells is essential to meet the serious clinical, therapeutic, and national-security challenges confronting virology today. We report the development of DNA aptamers as probes for the selective targeting of virus-infected living cells. METHODS To create aptamer probes capable of recognizing virus-infected cell...

Sequences homologous to the oncogene sequences of acute RNA tumor viruses have been shown to be highly conserved within vertebrates. In the present work, eight different oncogene DNA sequences have been used as probes to search for homologous sequences in the DNA of organisms of other phyla. Five of these probes hybridized to the DNA of Drosophila melanogaster. Abelson leukemia virus probe dete...

Oral squamous papilloma is a benign epithelial tumor that constitutes around 2.5% of all oral verruco-papillary lesions and caused by the Human Papilloma Virus (HPV). HPV subtypes 6 11, which are considered to be low carcinogenic potential usually associated with papilloma. Though there no site predilection as such, most common intraoral sites reported tongue, lips, buccal mucosa, gingiva, pala...

These studies make plain that the Shope papilloma virus induces the production of an arginase in rabbit squamous epithelium, and provide evidence that the information for the synthesis of the enzyme is derived from the virus rather than the rabbit. This form of induction is therefore different from that brought about by chemicals such as galactosides (36). Striking differences were shown betwee...

To cite: Singh AP, Jain S, Chaitra TR, et al. BMJ Case Reports Published online: 2 January 2013 doi:10.1136/ bcr-2012-007708 DESCRIPTION Oral squamous papilloma is a benign proliferation of the stratified squamous epithelium, which results in a papillary or verrucous exophytic mass induced by human papilloma virus (HPV). 2 A 51-year-old, healthy steel plant male worker reported with complaint o...

conclusions the high prevalence of hpv in abnormal cytology underlines to the fact that the presence of hpv is a critical factor in the development of cervical cancer. the use of hpv dna techniques could actually become an effective and fast means of ascertaining the presence of hpv in abnormal cytology. results result showed a 100% presence of high risk hpv in all the samples with abnormal cyt...

One of the most well studied biomarkers of HNSCC is human papilloma virus integration in oropharyngeal squamous cell cancers. Human papillomavirus (HPV) is a ~ 7.9-kb, nonenveloped, double-stranded, circular DNA virus that has been implicated in a variety of anogenital and aerodigestive diseases, ranging from common warts to laryngeal papilloma to cervical cancer. Currently, sequences for over ...