Daytime oral melatonin typically exerts soporific and thermoregulatory effects; however, it is not clear whether these effects reflect the normal physiological response to endogenous nocturnal melatonin production. We infused melatonin at doses that produced physiological and supraphysiological steady-state levels in 24 young adults during two daytime bed rest protocols. From 1000 to 1630, subj...

For a number of reasons, hospitals appoint fulltime and part-time physicians to practice medicine within the hospital or its outlying divisions. Such physicians provide a wide variety of primary, specialty, and subspecialty services. Among other advantages for hospitals are a potentially tighter rein on quality control and an increased bed occupancy and revenue at a time when financial issues h...

different control strategies of bed temperature and moisture were investigated using various inlet air temperatures and air fluxes in both the ordinary packed bed bioreactor (without cooling water in the jacket) and the bioreactor with cooling water in jacket. the experiments were carried out within a 1-l solid-state packed bed bioreactor in which aspergillus niger was cultivated on wheat bran....

The effects of earlier surgery and shorter bedrest on the outcome in 338 consecutive patients with subarachnoid haemorrhage admitted within five years to a primary emergency hospital were evaluated. Mortality from rebleeds diminished more than surgical mortality increased. Shortened bedrest did not increase the number of rebleeds in patients not operated on. The combined mortality from rebleed ...

GROSS, JOSEPH F., MARCOS INTAGLIETTA, AND BENJAMIN W. ZWEIFACH. Network model of pulsatile lzemodynamics in the microcirculation of the rabbit omentum. Am. J. Physiol. 226(5) : 1117-l 123. 1974.-Pulsatile pressure and red cell velocities were measured throughout the microvasculature of the rabbit omentum as a function of the order of branching. The data were analyzed in terms of a network model...

Numbers of patients undergoing coronary angiography and angioplasty procedures have increased in England due to targets within the National Service Framework for Coronary Heart Disease. Little evidence is available regarding optimal bed-rest duration for patients post-femoral arterial sheath removal following these procedures. Through literature review and clinical benchmarking, we aimed to ide...

CONTEXT It is not yet clear whether the diurnal variation in testosterone is regulated by circadian or homeostatic (sleep) influences. OBJECTIVE The present study tested whether testosterone is driven by a circadian-independent sleep effect by shifting sleep acutely to daytime in a 24-h sampling regiment. DESIGN, SETTING, AND PARTICIPANTS In the sleep laboratory, seven healthy young men (ag...

natal bed rest may actually have a deleterious effect upon fetal growth and well-being and that until this basic problem is settled it is not possible to say whether the better results obtained by Dr. Varma and Professor Curzen in their decompressed patients are more likely to have been effected by the dcompression itself or by the lesser amount of enforced bed rest to which they were subjected...