Iron deficiency anemia afflicts 1 in 3 individuals, mostly women and children worldwide. A novel application using iron-oxide nanoparticles (IONPs) and a photonic crystal (PC) optical biosensor as an immunodiagnostic platform for detection of serum ferritin, a biomarker for iron deficiency, is presented. Human liver ferritin (450 kDa), clinical serum controls, and three commercially available f...

The acetylation of p-aminobenzoic acid (PAB) (2) and of sulfanilamide (3) by the rat has been shown to depend upon an adequate supply of pantothenic acid, a constituent of the coenzyme A molecule (4). In addition the extent of acetylation is decreased by giving large amounts of PAB with reference to the size of the animal (5, 6) and to a smaller extent by a deficiency of riboflavin (5). The pre...

Three systems of immunoradiometric assays (IRMAs), a two-site monoclonal antibody sandwich IRMA (MAb-IRMA), two-site polyclonal antibody-monoclonal antibody sandwich IRMA (PAb-MAb-IRMA), and two-site polyclonal antibody sandwich IRMA (PAb-IRMA), were developed to detect low-grade infections with Plasmodium falciparum. The assays showed good correlation with parasitemia when tested against paras...

A new competitive immunochromatography (ICG) strip test based on polyclonal antibody (pAb) conjugated with gold nanoparticles (NPs) was developed and its applications for primary screening of immunoglobulin (Ig) A in serum were evaluated. Nanocolloidal gold as the detection reagent, with an average particle diameter of 20 nm, was synthesized and labelled pAb. The antibody-nanocolloidal gold pro...

Purpose: Among all known human coronaviruses, some viruses (e.g., SARS-CoV-2) cause severe pneumonia or even death. With the regard to its spread and importance of rapid identification/treatment, because pAbs are relatively cheap, able bind more sites on antigens neutralize them, this study was done for production purification anti-SARS-CoV-2 polyclonal antibodies (pAb) in rats. Methods: Viral ...

BACKGROUND Right ventricular (RV) diastolic function has been associated with outcomes for patients with pulmonary hypertension; however, the relationship between biomechanics and hemodynamics in the right ventricle has not been studied. METHODS AND RESULTS Rat models of RV pressure overload were obtained via pulmonary artery banding (PAB; control, n=7; PAB, n=5). At 3 weeks after banding, RV...

INTRODUCTION This study examined the injury prevention effectiveness of the parachute ankle brace (PAB) while controlling for known extrinsic risk factors. METHODS Injuries among airborne students who wore the PAB during parachute descents were compared with injuries among those who did not. Injury risk factors from administrative records included wind speed, combat loads, and time of day (da...

In many patients with congenital heart disease, the right ventricle (RV) is subjected to abnormal loading conditions. To better understand the state of compensated RV hypertrophy, which could eventually progress to decompensation, we studied the effects of RV pressure overload in rats. In the present study, we report the biventricular adaptation to 6 wk of pulmonary artery banding (PAB). PAB re...

The p53 tumor suppressor protein is an important regulator of cell proliferation and apoptosis. p53 can be found in the nucleus and in the cytosol, and the subcellular location is key to control p53 function. In this work, we found that a widely used monoclonal antibody against p53, termed Pab 1801 (Pan antibody 1801) yields a remarkable punctate signal in the cytoplasm of several cell lines of...

1 0-7803-7651-X/03/$17.00 © 2003 IEEE 2 IEEEAC paper #1197, Updated December 10, 2002 Abstract—Proposed satellite constellation networks, based on Geostationary Earth Orbit (GEO) satellites, Medium Earth Orbit (MEO), and Low Earth Orbit (LEO) systems, will be required to transport IP traffic and to provide quality of service (QoS). This paper proposes a new Diffserv-based scheme of IP bandwidth...