an efficient one-pot three-component procedure for the synthesis of new chiral spiro oxindolopyrrolidines/pyrrolizidines with highly regio- and diastereo-enantio, selective from 1,3-dipolar cycloaddition of azomethine ylides and chiral menthol-drived trans-cinnamic are described. the mechanism of the reaction is discussed on basis of the assignment of the absolute configuration of one of the cy...

for the first time b-podands have been studied as an efficient and powerful catalysts in the ring opening of epoxides with azide anion in water. the reaction afforded the corresponding 1,2-azidoalcohols with high regioselectivity under mild reaction conditions and in a highly atom economic fashion.

sizing of paperboard has a distinctive position in packaging grade paperboard material. optimization of sizing by alum-rosin at neutral ph in 4 layered paperboard (330 g/m2) wereevaluated in this study to find the optimum ratio of alum- rosin loading in the process. fixed amount of 1% cationic dispersed rosin together with alum as a fixing agent at 5 different levels of 1, 1.5, 2, 3, and 4% (ba...

myeloperoxidase (mpo) and paraoxonase-1 (pon1) are inflammatory and anti-inflammatory enzymes, respectively that have been involved in the pathogenesis of coronary artery disease (cad). in this study we sought to evaluate the relations of mpo and pon1 with high density lipoprotein (hdl) mean size in patients with acute coronary syndrome (acs). collectively, 50 control subjects and 50 patients w...

cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-cda) on the breast cancer cell line, mcf-7 (estrogen receptor positive, er+). mtt assay, annexin v-fluorescein/pi and hoechst 33...

background: hydroxymethylfurfural (hmf) is a common maillard reaction product directly formed from dehydration of sugars under acidic conditions during heating and storage in carbohydrate rich foods. the aim of the present study was to detect and quantify the amount of hmf in date syrup by hplc method. in addition, the amount of hmf in date syrup produced by traditional and industrial methods w...

background and aim: 2,4-dichlorophenol (dcp) is a compound  generated in a variety of industrial processes and also by chlorine disinfection of water polluted with phenolic compounds . dumping of dcp into the environment and water resources is of great concern because of the compound's intense odor and toxicity. dcp is very soluble and resistant to biodegradability so it cannot be removed ...