Background: This analysis reports the impact of eptinezumab on work productivity and daily activities in patients with migraine prior preventive treatment failures. Methods: The DELIVER study (NCT04418765) randomized adults documented evidence 2-4 failures to receive 100mg, 300mg, or placebo (IV every 12 weeks). At baseline 4 weeks, completed migraine-specific 6-question Work Productivity Activ...

BACKGROUND Vocal cord leukoplakia comprises a variety of lesions. The purpose of this study was to stratify vocal leukoplakias before surgery. METHODS Patients with an initial diagnosis of vocal leukoplakia who underwent surgical excision at a tertiary referral center in Taiwan were recruited for this study. Their clinical records, including age, sex, preoperative laryngoscopic images in the ...

BACKGROUND HPV types vary by country and HIV status. There are no data on the prevalent HPV genotypes from Cameroon. METHODS We conducted a cross-sectional, observational study on 65 Cameroonian women. Samples were sent for HPV genotyping and Thin Prep analyses. RESULTS 41 out of 61 samples tested (67.2%) had HPV subtypes detected. The most common high risk types encountered were: 45 (24.6%...

AIM To evaluate the effect of a preparation with bacterial ribosomes and proteoglycans from Klebsiella pneumoniae «R» on the in vitro expression of CD11c and CD103 molecules in neutrophils from peripheral blood. METHODS Isolation of neutrophils from peripheral blood with Ficoll-Paque, incubation with R and detection of CD11c and CD103 through flow cytometry. RESULTS Six hours after the incu...

Introduction Genome-wide association studies (GWAS) are a powerful means for identifying genes with disease-associated common variants, but they are not well-suited to detect genes with disease-associated rare or low-frequency variants. It has long been debated whether the innate immune system is involved in the pathogenesis of Behçet’s disease (BD) but genetic evidence to support this hypothes...

BACKGROUND To investigate the relationship between paraglottic space (PGS) invasion and lymph node metastasis in patients undergoing supracricoid partial laryngectomy. METHODS The study included 98 subjects with squamous cell carcinoma of the glottis. RESULTS The PGS invasion rate was 60.2% (59/98), and a significant correlation was found between PGS invasion and cervical lymph node metasta...

fConttnua on ravaraa alda It nacaaaary and Idantity by block numbar)The problem of "assuring interactive consistency" is defined in [PSL].20 It is assumed that there are n isolated processors, of which at most m arefaulty. The processors can communicate by means of two-party messages, usinga medium which is reliable and of negligible delay. The sender of a messageis always i...

This study assessed the epidemiologic characteristics of acute viral gastroenteritis in hospitalized children. A stool sample obtained from each child was analyzed for the presence of astrovirus, calicivirus, rotavirus, adenovirus, enterovirus, and digestive bacteria. Of the 438 stool samples obtained, 138 tested positive for > or =1 pathogen during the winters of 1997-1998 and 1998-1999 (P<.00...

Presence of early secretory antigenic target-6 (ESAT-6)-specific, interferon- gamma -secreting T cells in blood accurately marks tuberculosis infection. In tuberculous pleural effusions from 10 patients with tuberculosis, these cells were concentrated a mean of 15-fold (standard deviation, +/-6-fold), relative to their level in peripheral blood (P=.014), and displayed rapid effector function. S...