Our laboratory previously reported that active glottal closure was present in 90% of spontaneous central apneas in premature lambs while maintaining a high-apneic lung volume (Renolleau S, Letourneau P, Niyonsenga T, and Praud JP. Am J Respir Crit Care Med 159: 1396-1404, 1999.) The present study aimed at testing whether this mechanism limits postapnea oxygen desaturation. Four premature lambs ...

OBJECTIVE: To verify the association between oxygen desaturation episodes and the dips in pH in infants with chronic obstructive respiratory symptoms. METHOD: Cross-sectional study with children 24 months old or younger hospitalized for investigation of chronic obstructive respiratory symptoms from 1997 to 1999. The patients underwent esophageal pH monitoring associated with transcutaneous oxyg...

BACKGROUND Neuropsychological and neurological deficits are still major causes of mortality and morbidity after cardiac surgery. These complications are thought to be caused by embolisms and cerebral hypoxia. Thus, continuous neuromonitoring is essential during cardiac surgery due to cerebral oxygen desaturation during different periods. Near-infrared spectrophotometry (NIRS), a non-invasive me...

The incidence of immediate postoperative hypoxaemia following general anaesthesia was studied using a pulse oximeter in 120 ASA category I and II patients during transport to the recovery room. Thirty-two percent of those not given oxygen during transport developed desaturation (SaO2 less than 90%) in spite of receiving 100% oxygen for 5 min before transport. In 14.3% of patients SaO2 decreased...

BACKGROUND Currently the common pathogenetic mechanisms in nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) are gaining increased attention. The aim of this study is to find out the influence of chronic intermittent hypoxemia and OSA related parameters to the severity of NAFLD. METHODS We examined the liver functions tests and ultrasonographic data of liver as well ...

BACKGROUND The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2011 update recommends that the management and treatment of COPD be made to combine the impact of disease and future risk of exacerbation. These patients have worsening quality of life and limitation of activities of daily living (ADLs), which can be manifested as a decrease in S(pO2) and progressive dyspnea. The aim o...

This paper presents a new approach for evaluating predictions of oxygen saturation levels in blood ( SpO2). A performance metric based on a threshold is proposed to evaluate  SpO2 predictions based on whether or not they are able to capture critical desaturations in the  SpO2 time series of patients. We use linear auto-regressive models built using historical  SpO2 data to predict critical desa...

To the Editor:—Naguib et al. have presented a clinically relevant study of arterial saturation values after preoxygenation and different doses of suxamethonium, and discuss their results using the extensive reports relevant to this topic. Unfortunately, they perhaps did not search the published work back to times before the pulse oximeter was introduced. Before the pulse oximeter, the Hewlett P...