The aim of this study was to determine the antioxidant properties of 6,7-dihydroxy-3,4-dihydroiso- quinoline-3-carboxylic acid (1) and its derivatives in living cells against reactive forms of oxygen and nitrogen, i.e., hydrogen peroxide and nitric oxide. Four of tested compounds scavenged the reactive form of nitrogen more efficiently or similarly to Trolox (EC50 = 55.80 µM). Two compounds exh...

Oxygen storage/release (OSC) capacity is an important feature common to all three-way catalysts that enables them to efficiently remove harmful compounds such as hydrocarbons, CO and NOx in automotive exhaust gases. In this report, three types of CeO2-ZrO2 (Ce:Zr = 1:1 molar ratio) compounds with different OSC were characterized by means of XRD (X-ray diffraction) and XAFS (X-ray absorption fin...

New important applications of copper metal, e.g., in the areas of hydrogen production, fuel cell operation, and spent nuclear fuel disposal, require accurate knowledge of the physical and chemical properties of stable and metastable copper compounds. Among the copper(I) compounds with oxygen and hydrogen, cuprous oxide Cu(2)O is the only one stable and the best studied. Other such compounds are...

The replacement of oxygenated functionality (hydroxy and alkoxy) with a fluorine atom is commonly used bioisosteric in medicinal chemistry. In this paper, we use molecular matched-pair analysis to better understand the effects on lipophilicity. It seems that reduced log P compound normally dominant determining size difference. We observe presence additional electron-donating groups an aromatic ...

Microbial mats are characterized by high primary production but low growth rates, pointing to a limitation of growth by the lack of nutrients or substrates. We identified compounds that instantaneously stimulated photosynthesis rates and oxygen consumption rates in a hypersaline microbial mat by following the short-term response (c. 6 h) of these processes to addition of nutrients, organic and ...

Petroleum refineries utilize thermal cracking, catalytic cracking and hydrogenation processes to produce high quality oil products. Hydrodesulfurization is one of the most important methods to remove sulfur from petroleum fractions. Heavy oil contains various types of sulfur compound. The structure of the sulfur compounds affects the ease of sulfur removal1). Acyclic sulfur compounds including ...

introduction: active packaging is one of the innovations in food packaging industry that would be a respons to the changing needs of consumers and markets. in this technique, materials such as adsorbents oxygen, moisture, carbon dioxide, ethylene and carbon dioxide-releasing flavor compounds, antimicrobials, antioxidants and various aromatic compounds are used. in the last decade, great attenti...

Hemoglobin (Hb) modifiers that stereospecifically inhibit sickle hemoglobin polymer formation and/or allosterically increase Hb affinity for oxygen have been shown to prevent the primary pathophysiology of sickle cell disease (SCD), specifically, Hb polymerization and red blood cell sickling. Several such compounds are currently being clinically studied for the treatment of SCD. Based on the pr...

Recently, copper has been shown to be capable of mediating the activation of several xenobiotics producing reactive oxygen and other radicals. Since copper exists in the nucleus and is closely associated with chromosomes and DNA bases, in this study we have investigated whether the activation of 1,4-hydroquinone (1,4-HQ) and a variety of other phenolic compounds by copper can induce strand brea...