The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.

BACKGROUND Different types of carbon nanotubes may represent toxic hazards due to their size distribution and massive surface area. They may adsorb other toxic agents that can consequently be transported into the body. Hence the aim of this study was to confirm or reject the hypothesis of carcinogenicity of two types of carbon nanotubes. MATERIALS AND METHODS Well-defined single-walled and mu...

Vertically aligned single-walled carbon nanotubes (VA-SWNTs) have been synthesized by an Alactivated plasma-enhanced chemical vapor deposition (PECVD) method. On this basis, we have developed a facile but effective method for direct growth of multicomponent micropatterns of VA-SWNTs interposed within the patterned areas surrounded by vertically aligned multi-walled carbon nanotubes (VA-MWNTs) o...

carbon nanotubes are regarded as promising building blocks for the construction of novel biosensors due to their unique properties like fast electron transfer, high electrocatalytic effect and good biocompatibility. in the present study, the effect of different chemical oxidation’s methods of multi-walled carbon nanotubes (mwcnts) on the electrochemical behavior of modified graphite electrodes ...

aim : the aim of this study is to design multi-walled carbon nanotubes (mwcnts) loaded with paclitaxel (ptx) anti-cancer drug and investigate its anti-cancerous efficacy of human gastric cancer. the sidewall surfaces of pristine mwcnts are highly hydrophobic. a major goal in carbon nanotube chemistry has been functionalization for aqueous solubility, and exploiting nano-tubes as macromolecules ...

Control over chemical functionalization is a crucial point in the field of nanotechnology. Herein, we present the covalent functionalization of several carbon nanoforms (single-walled carbon nanotubes, double-walled carbon nanotubes, multi-walled carbon nanotubes and carbon nanohorns) by means of diphenyl dichalcogenides. These ones show different reactivity to the nanomaterials and are able to...

Carbon nanomaterials are a new form of carbon based materials which have been receiving much attention for their interesting properties over the past three decades. The materials were initially discovered in 1952 [1] but were only scientifically recognized in 1991 when Iijima submitted a report [2]. An interesting feature of these allotropes of carbon has been the different forms in which they ...

in this paper, the chemical functionalization of carboxylated multi-walled carbon nanotubes (mwnt-cooh) by 1,2-phenylenediamine, have been investigated. mwnt-benzimidazole is obtained through mwnt-amide reaction with pocl3 after 72h, which is confirmed by ft-ir, sem, tga, and elemental analysis. these functionalizations have been chosen due to –nh2 and nhco active sites in mwnt-amide for future...

Various proteins adsorb spontaneously on the sidewalls of acid-oxidized single-walled carbon nanotubes. This simple nonspecific binding scheme can be used to afford noncovalent protein-nanotube conjugates. The proteins are found to be readily transported inside various mammalian cells with nanotubes acting as the transporter via the endocytosis pathway. Once released from the endosomes, the int...

By using alcohol as the carbon source, a new simple catalytic chemical vapor deposition technique to synthesize high-purity single-walled carbon nanotubes at low temperature is demonstrated. Because of the etching effect of decomposed OH radical attacking carbon atoms with a dangling bond, impurities such as amorphous carbon, multi-walled carbon nanotubes, metal particles and carbon nanoparticl...