BACKGROUND Many changes can occur in proteins, including amino acid modification, fragmentation, changes in absorption and fluorescence spectra and others. All these modifications can be used as markers of protein damage by free radicals. AIM OF THE WORK The aim of the present study was to investigate the antioxidant activities of the aqueous extracts of dry green of pods Phaseolus vulgaris, ...

OBJECTIVE To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns. METHOD Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC) and individual antioxidant components: vitamin C, uric acid, albumin, thio...

results a significant higher serum pab value was observed in shift working and daytime nurses (152.28 ± 43.64 hk) in comparison to the control group (63.64 ± 34.41 hk index), p value = 0.001. in day time nurses, also serum pab between male (119.09 ± 47.14 hk) and female (162.53 ± 37.02 hk) in nursing workers was significant, p value = 0.005. in the night shift working nurses, there was also a s...

objective: crocin, the carotenoid isolated from saffron, has numerous medicinal properties which include anticancer and antioxidant activities. some antioxidants, such as carotenoids, can act as pro-oxidants at higher dosages and therefore induce tissue damage. in this situation antioxidant defense systems in the liver activate to prevent tissue damage. this study investigates the possible toxi...

BACKGROUND AND OBJECTIVES Oxidant damage is an important contributor to the premature destruction of erythrocytes and anemia in thalassemias. To assess the extent of oxidant damage of circulating erythrocytes and the effects of antioxidant therapy on erythrocyte characteristics and anemia, we used a mouse model of human beta-thalassemia intermedia (b1/b2 deletion). DESIGN AND METHODS Several ...

Background: Chronic kidney disease (CKD) is a widespread public health problem, which may have several adverse consequences such as renal failure, cardiovascular disease, and premature death. Kidney-related pathologies increasing prevalence rates, produce considerable financial burden, are characterized by elevated levels of oxidative stress (OS). Several markers emerged well-suited indicators ...

background: imbalances between the oxidant-antioxidant status have been implicated in the pathogenesis of several diseases, including oral cancer. majority of oral cancer are preceded by a well-recognized group of pre-malignant lesions. however, only a small fraction of those lesions, undergo malignant transformation. hence, there is a great need to identify biological markers, which will assis...

BACKGROUND The aim of this study was to investigate the levels of oxidative stress including total oxidant status, total antioxidant status, and paraoxonase activity in patients with a diagnosis of acute appendicitis. METHODS Seventy-three patients who underwent surgery with a preoperative diagnosis of acute appendicitis (Group I) were included into the study. The control group (Group II) con...

abstract background and objective: diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. we aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (tos) and total antioxidant (tas) status in the cardiac tissue of diabetic rats. material and methods: fourty-two male wistar rats with an average wei...

Oxidative stress has been implicated as a mechanism underlying hyperglycaemia-associated cellular damage and could play a role in the development of diabetes-related complications. This study aimed to evaluate the significance of changes in oxidant-antioxidant status in 176 child and adolescent diabetic patients at clinical onset, during disease progression and when early microvascular complica...