نتایج جستجو برای: ovarian dysfunction

تعداد نتایج: 238560  

Journal: :International Journal of Gynecological Cancer 1997

Journal: :Journal of Reproduction and Development 1998

Journal: :Egyptian Academic Journal of Biological Sciences. C, Physiology & Molecular Biology 2022

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Karina Dahl Steffensen Marianne Waldstrøm Dorte Aalund Olsen Thomas Corydon Karen Axelgaard Lorentzen Hans Jørgen Knudsen Ulla Jeppesen Ivan Brandslund Anders Jakobsen

PURPOSE Dysfunction of the epidermal growth factor (EGF) complex is essential to the growth and development of many human tumors. Overexpression of the EGF receptor (EGFR) is a characteristic finding in a considerable number of solid tumors and often signalizes poor prognosis. There is a major disagreement among researchers about both the frequency and possible clinical importance of EGFR overe...

Journal: :Medical science monitor : international medical journal of experimental and clinical research 2015
Xiaogang Liu Lihong Ma Qinhua Rao Yuhui Mao Yuhong Xin Huiqin Xu Changju Li Xiaoyan Wang

BACKGROUND Ovarian cancer is the most lethal gynecological malignant cancer in the female genital system. The dysfunction of miRNA contributes to ovarian cancer development. MATERIAL AND METHODS The miR-1271 level in ovarian cancer tissues and cells was assayed by qRT-PCR. The miR-1271 expression in cells was overexpressed by miRNA-mimic transfection and reduced by miRNA-antisense-oligonucleo...

2013
Fang-Fang Bi Da Li Chen Cao Chun-Yan Li Qing Yang

BACKGROUND Both BRCA1 and angiotensin II type 1 receptor (AGTR1) play a critical role in ovarian cancer progression. However, the crosstalk between BRCA1 and AGTR1 signaling pathways remains largely unknown. METHODS BRCA1 promoter methylation was analyzed by bisulfite sequence using primers focused on the core promoter region. Expression levels of BRCA1 and AGTR1 were assessed by immunohistoc...

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