PURPOSE Androgen replacement therapy has been shown to be safe and effective for most patients with testosterone deficiency. Male partners of infertile couples often report significantly poorer sexual activity and complain androgen deficiency symptoms. We report herein an adverse effect on fertility caused by misusage of androgen replacement therapy in infertile men with hypogonadal symptoms. ...

today power consumption is considered to be one of the important issues. therefore, its reduction plays a considerable role in developing systems. previous studies have shown that approximately 50% of total power consumption is used in cache memories. there is a direct relationship between power consumption and replacement quantity made in cache. the less the number of replacements is, the less...

in recent years, rye caused heavy damages in wheat farms in iran. in order to evaluate wheat competitiveness ability against rye, an experiment was conducted in replacement series design. field experiment was carried out at the agricultural and natural resources research station in miandoab during 2009-2010 (for 2 years). the experimental design was a randomized complete block design with 3 rep...

1. Preparations of rabbit serum albumin, dialysed against rabbit plasma, were incubated at temperatures in the range 3949°C at pH 7.3 and pH values in the range 7.2-8.0 at 43°C. 2. Denaturation of the rabbit albumin was studied by measuring (a) its susceptibility to tryptic hydrolysis and (b) catabolic rates in rabbits. 3. The rabbit albumin was demonstrated to denature by both criteria. 4. Ass...

Exposure to microgravity (weightlessness) is known to cause rapid bone and muscle losses. We have used the hind limb-suspended (HLS) rat model to simulate microgravity-induced musculoskeletal losses in order to assess resulting hormonal changes and to develop a novel pharmacological countermeasure. Previously, we demonstrated significant decreases in circulatory hormonal levels [serum thyroxin,...

The granite stone is the most widely used in the construction and granite slurry is generated through cutting and polishing of the stone. Granite slurry is waste material consisting of very fine powder and creats disposal and environmental problems in worldwide today. Disposal of granite waste leads to health hazards like respiratory and allergy problems to the people around. It also causes the...

Although muscle metabolism and exercise capacity seem to be affected in patients with subclinical hypothyroidism, there is little evidence indicating improvement of the exercise tolerance due to levothyroxine (L-T(4)) replacement. The aim of the present study was to verify possible cardiopulmonary changes during exercise in patients with subclinical hypothyroidism on L-T(4) replacement with a n...

Developmental changes in the GH-insulin-like growth factor I (IGF-I) axis were evaluated in female rhesus monkeys to test the hypothesis that estradiol differentially regulates IGF-I secretion and molar ratios of IGF-I to IGF-binding protein-3 (IGFBP-3) from adolescence into adulthood and that estradiol can reestablish GH secretion in the face of enhanced IGF-I negative feedback inhibition of G...

Background: This study examined the pharmacokinetic profile of prednisolone. Methods: Using a newly developed ultra-performance liquid chromatography MS/MS method, prednisolone profiles in healthy volunteers and patients with adrenal insufficiency already treated with prednisolone were prospectively analyzed in a tertiary center. Results: Twelve prednisolone day curves were analyzed. Six patien...

In adult female monkeys, serum concentrations of insulin-like growth factor I (IGF-I) are decreased by estradiol replacement, whereas levels of IGF-binding protein-3 (IGFBP-3) are increased. Furthermore, chronic IGF-I supplementation elevates serum IGFBP-3 despite a suppression of GH. To better understand how estradiol and IGF-I affect the IGF-I axis, a series of three studies was conducted to ...