نتایج جستجو برای: osthole
تعداد نتایج: 222 فیلتر نتایج به سال:
BACKGROUND Osthole (Ost), a natural coumarin derivative, has been shown to inhibit many pro-inflammatory mediators and block voltage-gated Na+ channels. During inflammation, acidosis is an important pain inducer which activates nociceptors by gating depolarizing cationic channels, such as acid-sensing ion channel 3 (ASIC3). The aim of this study was to examine the effects of Ost on nucleus pulp...
Alzheimer disease (AD) is a complex neurodegenerative disease that leads to the decline in the cognition in elderly people (>65 years of age). Deposition of senile plaques (of amyloid β) and neurofibrillary tangles (of hyperphosphorylated tau) are the typical hallmarks of the disease. AD significantly contributes to the worldwide dementia, which is 46.8 million in 2015 and estimated to 131.5 mi...
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