Chronic recurrent multifocal osteomyelitis is a rare inflammatory form of osteomyelitis of unknown etiology. It affects children and adolescents, and signs and symptoms include recurrent episodes of bone pain, tenderness, possible constitutional upset, and increased inflammatory markers. We present 2 patients with cases of chronic recurrent multifocal osteomyelitis affecting the sacrum who resp...

BACKGROUND Coagulation and fibrinolysis are important in infections and systemic inflammatory response syndrome. Polymorphisms in plasminogen activator inhibitor-1 (PAI-1, SERPINE1) and tissue plasminogen activator (tPA, PLAT), such as PAI-1 (-675 4G/5G deletion/insertion) and tPA (Alu insertion/deletion [I/D]), are associated with strokes, myocardial infarctions, bacterial infections and septi...

BACKGROUND There is increasing recognition that deep venous thrombosis (DVT) is a complicating factor in some children with acute hematogenous osteomyelitis. The similarity in signs and symptoms of osteomyelitis and DVT make clinical recognition of this complicating condition difficult. It would be helpful to the clinician to identify by other means which children with osteomyelitis are at grea...

INTRODUCTION Pubic osteomyelitis is a rare type of suppurative osteomyelitis. Early diagnosis of pubic osteomyelitis is difficult, and prolonged inflammation results in progressive bone degradation, severe pelvic pain and a wide-based gait. PRESENTATION OF CASE We report the case of an 82-year-old woman who was admitted to a previous hospital with severe abdominal pain caused by a perforated ...

AIM To evaluate the course of group A streptococcal osteomyelitis associated with severe disease nowadays. METHODS Three consecutive cases of severe group A streptococcal disease with osteomyelitis in children that were documented in Beer Sheva, Israel are described in detail. RESULTS Two of the three cases were postvaricella. Early in the course of the disease, the presentation resembled t...

Thoracic empyema and vertebral osteomyelitis is a rare combination. We report a case of vertebral osteomyelitis possibly caused by a progressive thoracic empyema. The causative pathogen was Escherichia coli. Computed tomographic (CT) scan and magnetic resonance imaging (MRI) suggested the diagnosis of vertebral osteomyelitis, confirmed by transthoracic needle aspiration and operative findings. ...

Introduction: SAPHO syndrome is defined as the association of a group of rare sterile osteoarticular disorders and inflammatory skin diseases whose etiology, although not yet determined, probably involves genetic, immunological and infectious mechanisms. The recurrent multifocal osteomyelitis, an inflammatory disease, can be associated with this syndrome even as a single event.  Case Report:...

Bone scan in diagnosis of infectious osteoarthritis  Bone scan with Technezium 99m is harmless methodoi evaluation of Skeletal lesions.It is safe 1n pedia­_ trics age group and it can be used in early diffe-rentiate osteomyelitis from cellulits sand also it may help in diagnosis of subsclinical  involvement of  eumatoid arthritis,benign and malignant bone  tumors stress fractures and periostit...

Abstract Background Staphylococcus aureus is a leading cause of antibiotic-resistant bacterial infections and can infect nearly every organ the human body. One common manifestation S. disease invasive bone infection, or osteomyelitis. Osteomyelitis one most difficult to treat infections, often necessitating prolonged antibiotic treatment surgical interventions. Hyperglycemia, elevated blood glu...

INTRODUCTION Chronic recurrent multifocal osteomyelitis is a rare, systemic, aseptic, inflammatory disorder that involves different sites. Pathogenesis of chronic recurrent multifocal osteomyelitis is currently unknown. CASE PRESENTATION A two-year-old Caucasian boy, diagnosed with chronic recurrent multifocal osteomyelitis with granulomatous pyoderma following routine vaccinations is present...