Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated celiac disease. Osteomalacia complicating celiac disease had become more and more rare. We describe here a case of osteomalacia secondary to a longs...

Hypophosphorous osteomalacia (HO) is a rare metabolic disease. Due to hypophosphatemia and insufficient production of active vitamin D, the bone matrix can not be mineralized normally. Its clinical symptoms are atypical. It generally manifested in pain muscle weakness different parts. With progress disease, it very easy have osteoporosis, pathological fracture, deformity damage function other o...

In this study 201 elderly patients with femoral neck fractures were compared with 30 osteomalacic patients with the same injury. Hypocalcaemia and a raised alkaline phosphatase level are common biochemical abnormalities in elderly patients with femoral neck fractures. In only a minority of patients, however, were they associated with histologically proven osteomalacia. By using the combination ...

Osteomalacia is a condition characterised by failure of bone mineralisation. While abnormalities of vitamin D supply, metabolism or action are the most common and well-known causes, chronic phosphate deficiency, due to either insufficient input (intake or absorption) or renal losses are also important causes of rickets or osteomalacia.1 Hypophosphataemia also commonly co-exists with vitamin D d...

Osteomalacia is one of the most common osteometabolic diseases among the elderly and may be associated with osteoporosis. It is typically caused by lack of vitamin D and is characterized by mineralization deficiency of the osteoid matrix in the cortical and trabecular bone, resulting in accumulation of osteoid tissue. Vitamin D deficiency is a pathogenic factor of osteoporosis that can be modif...