The findings in 40 children (24 female, 16 male) with osteoarticular complications of brucellosis are presented. Raw milk was the main source of infection. Most patients had acute onset of fever, arthralgia, and myalgia. Arthritis was the presenting symptom in all patients, of whom two also had osteomyelitis. Arthritis was monoarticular in 28 (70%) of 40 cases with predilection for large weight...

Acromegaly is caused by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-I (IGF-1) due to pituitary tumor. Other causes, such as increased growth-hormone releasing hormone (GHRH) production, ectopic GHRH production, and ectopic GH secretion, are rare. Growth hormone and IGF-1 play a role in the regulation of bone metabolism, but accurate effect of growth horm...

conclusions extrapulmonary tuberculosis may mimic many other diseases, so it should be kept in mind in the differential diagnosis. it is essential to diagnose osteoarticular tuberculosis early, as late diagnosis or inadequate treatment may cause permanent disability. case presentation a 16-year-old girl presented to the outpatient otolaryngology clinic with painless swelling of the neck, and to...

Yokenella regensburgei belongs to the family Enterobacteriaceae and is an opportunistic agent rarely associated with infections in humans. We report a case of osteoarticular knee infection caused by Y. patient under treatment for rheumatoid arthritis, using corticosteroids, complication primary total arthroplasty knee. was identified VITEK2 system. Antimicrobial susceptibility testing performed...

We report the clinicoradiological features of tuberculosis in the clavicle in 4 patients. The patients' ages ranged from 9 months to 29 years. All patients were managed with antitubercular drug therapy for one year and one underwent surgical debridement and curettage as well. Clinicians should be aware of the varied presentation (pain, non-healing ulcer, abscess, multifocal osteoarticular tuber...

i f l p j s t hondrolysis of the glenohumeral joint has been reorted to occur after the use of thermal energy, bioaborbable intraarticular implants, intraarticular infusion of upivacaine, and intraarticular injection of gentian vioet dye, as well as after otherwise uncomplicated cases f shoulder arthroscopy during which no such etiologic actors can be identified. Chondrolysis can esult in devas...

We present a case of Kashin-Beck Disease primarily affecting the ankles. Our findings are consistent with other reports of the symptoms, incidence, and progression of these diseases. At this time, our patient has chosen conservative treatment, but is considering eventual osteoarticular allografts. According to the available literature, surgical treatment is the only option that will not only al...

Alkaptonuria (AKU) results from defective homogentisate1,2-dioxygenase (HGD), causing degenerative arthropathy. The deposition of ochronotic pigment in joints is so far attributed to homogentisic acid produced by the liver, circulating in the blood and accumulating locally. Human normal and AKU osteoarticular cells were tested for HGD gene expression by RT-PCR, mono- and 2D-Western blotting. HG...

tomycin levels of 70% of serum is similar. In this case, however, daptomycin was assayed opportunistically, as the patient required repeat knee aspiration for culture after 2 weeks of therapy. It is probable, therefore, that the concentration of daptomycin in synovial fluid reflects either steady-state concentration or accumulation at the site of infection. The therapeutic daptomycin concentrat...