Osteogenesis is categorized into two groups based on developmental histology, intramembranous and endochondral ossification. The role of blood vessels during endochondral ossification is well known, while their role in intramembranous ossification, especially the intertissue pathway, is poorly understood. Here, we demonstrate endothelial Yap/Taz is a novel regulator of intramembranous ossificat...

choanal polyps are a form of nasal polyps that grow toward the choana with a single stalk. septochoanal polyp is a rare entity that originates from the mucosa of the nasal septum with choanal extension. the most common site of its origin is mainly the superior aspect of the posterior portion of the nasal septum. however, metaplastic ossification is a rare event in nasal polyp and to the best of...

BACKGROUND AND PURPOSE Endochondral ossification of the otic capsule is a process that continues postnatally; hence, incomplete endochondral ossification is seen as pericochlear hypoattenuation on temporal bone CT scans of children. We determined the prevalence and extent of this entity in a large series and assessed its relation to age and underlying sensorineural hearing loss. MATERIALS AND...

disodium glycyrrhetinic acid hemiphthalaic (gap) was evaluated for developmental toxicity in pregnant nmri mice. gap was administered intrapcritoneally on days s, 9, 10, of gestation at doses of 0, 25, 50 and 75 mg/kg/dav. on gestation day of is, after operational delivery, the fetuses were examined for soft tissue, external and skeletal defects. increased absorptions, dead fetuses, and reduce ...