I believe that multiple sclerosis progression could be stopped through antibiotics, dewormers, beta glucans and garlic extract and, by far the most difficult, changing quality of water ingested, or used for washing salads, in addition to increasing consumption probiotics. MS is due unfortunate encounter 3 diseases: intestinal dysbiosis, chlamydia infections orthopedic problems. However, how wou...

context a tourniquet is a device that is used frequently in most orthopaedic surgeries but this routine device can lead to serious complications so we decided to review and declare it for safe instruction and use. evidence acquisition we searched the word “tourniquet” in pubmed and google and reviewed all full text english articles and abstracts of non-english articles. in addition, we read all...

It is expected that in future, there will be an immense usage of implantable devices which will cause the number of infections to increase naturally because some patients are unable to autonomously prevent formation of bio film on implant surfaces. The ideal implant should be able to promote osteointegration, deter bacterial adhesion and minimize prosthetic infection. Recent developments in mat...

Infections of orthopedic implants are associated with high morbidity. The emergence of antibiotic resistant strains and the tendency of microbes to form biofilms on orthopedic devices prompt the individuation of novel antimicrobial agents. Silver nanoparticles represent an interesting alternative, but their effects on bone cells need to be clarified. We focused on osteoblast-like cells and on b...

Accurate diagnosis of orthopedic device-associated infections can be challenging. Culture of tissue biopsy specimens is often considered the gold standard; however, there is currently no consensus on the ideal incubation time for specimens. The aim of our study was to assess the yield of a 14-day incubation protocol for tissue biopsy specimens from revision surgery (joint replacements and inter...

In the US annually there are 600,000 joint prostheses and 2,000,000 fracture-fixation devices surgically implanted with an average rate of infection of 2% and 5% respectively for primary insertion. [1]. Infected orthopedic hardware is most successfully cured by a combination of prolonged antibiotics and surgical replacement, sometimes involving a 2-step operative procedure that incurs increased...

BACKGROUND Vitamin D deficiency has been associated with a high number of health outcomes, and its role on the immune system has been deeply investigated in recent years, although poor data are still available on vitamin D status in orthopedic infections including those of prosthetic implants. METHODS We focused on preoperative values of 25(OH)D in selected groups of patients with septic (Gro...

We hypothesized that less malalignment and complications occur with intramedullary nailing of distal third tibia fractures (42A, B, C) after the implementation of orthopedic trauma surgeons to this level II community hospital. We also hypothesized that patients with < or =5 degrees of malalignment have poorer function as measured by the MODEMS functional outcome scale. Two cohorts of distal thi...

The preoperative care of patients undergoing orthopedic surgery and treated with biologic agents is of great significance.Perioperative use of biologic agents could lead to such complications as infection and delayed postoperative woundhealing. This narrative review aimed to evaluate the current information on the use of biologic agents in patientsundergoing orthopedic surgery...