Organometallic compounds are widely used in almost all sectors of industry. as a result of emissions from natural and anthropogenic sources they are released to the environment, where they undergo a variety of conversions and interactions. some organometallic compounds exhibit high toxicity. organometallic compounds of mercury, tin, lead, selenium and arsenic are among the most common and hazar...

The ICEBAMO meetings aim to facilitate interdisciplinary discussion on environmental and biological aspects of main-group organometals. Previous meetings in Padua (1986 and 1991) and Bordeaux (1994) have brought together researchers from the fields of toxicology, environmental sciences, analytical chemistry, biochemistry, and synthetic organometallic chemistry. ICEBAMO 98 in Odense will provide...

Nucleophilic trapping of iminium salts generated via oxidative functionalisation of tertiary amines is well established with stabilised carbon nucleophiles. The few reports of organometallic additions have limited scope of substrate and organometallic nucleophile. We report a novel, one-pot methodology that functionalises N-substituted tetrahydroisoquinolines by visible light-assisted photooxid...

Abstract Shoes with polyester urethane soles have been stored for 3 decades in a museum environment after several months of mining use. Upon observation sole material ageing under natural conditions, the shoes were laboratory since 2017 order to evidence and follow signs degradation. This study aims at characterizing complex degradation found on museum’s collection. Combining chemical compositi...

Organometallic polymer research offers many potential academic and industrial rewards because of the number of elemental variations possible. Unfortunately, there are no general synthetic methods as found for carbon based polymers. Transition metal catalysed dehydrocoupling reactions may prove to be generally applicable to the synthesis of silicon based organometallic polymers. We report here o...

We disclose the synthesis, characterization, and catalytic application of a triphos-tagged, non-pincer-type tungsten complex. The pertinent W-based half-sandwich compound was used in homogeneous hydrogenation ketones esters to afford corresponding alcohols. Furthermore, introduced base metal catalyst facilitated conjugate reduction enoates yield respective CC-bond-free esters. Most applied subs...

Following the pioneering Ziegler addition of nucleophiles to nonactivated unsaturated carbon–carbon bonds, the controlled carbometallation reaction has emerged. Since then, reactions that result in the addition of a carbon–metal bond of an organometallic across a carbon–carbon unsaturated system, leading to a new organometallic in which the newly formed carbon–metal bond can be used for further...

BACKGROUND The serine/threonine kinase PIM2 is highly expressed in human leukemia and lymphomas and has been shown to positively regulate survival and proliferation of tumor cells. Its diverse ATP site makes PIM2 a promising target for the development of anticancer agents. To date our knowledge of catalytic domain structures of the PIM kinase family is limited to PIM1 which has been extensively...