Efficient and straightforward methods for the synthesis of fluorinated compounds are increasingly important in the discovery of new biologically active molecules and advanced functional materials. Over the past few years, considerable efforts have been made in the fluoroalkylation of arenes, however efficient strategies for the synthesis of alkenes bearing fluorinated functional groups are less...

Metal-pattern formation using vacuum evaporation is a critical process from basic research to industrial mass-production. Selective metal deposition metal-atom desorption an organic surface promising metal-patterning method by maskless deposition. In this study, we demonstrate metal-pattern for various species vacuum-depositable and printable perfluoropolyether (PFPE) based material. A PFPE-bas...

The investigation of unique chemical phenotypes has led to the discovery of enzymes with interesting behaviors that allow us to explore unusual function. The organofluorine-producing microbe Streptomyces cattleya has evolved a fluoroacetyl-CoA thioesterase (FlK) that demonstrates a surprisingly high level of discrimination for a single fluorine substituent on its substrate compared with the cel...

The ability of fluorine in a C-F bond to act as a hydrogen bond acceptor is controversial. To test such ability in complex RNA macromolecules, we have replaced native 2'-OH groups with 2'-F and 2'-H groups in two related systems, the Tetrahymena group I ribozyme and the ΔC209 P4-P6 RNA domain. In three cases the introduced 2'-F mimics the native 2'-OH group, suggesting that the fluorine atom ca...

The mechanism of anode-initiated breakdown in liquid organic dielectrics with long molecular chains is proposed on the basis experimental data high velocities channel propagation organosilicon and organofluorine liquids (~10 7 cm/s), which are comparable to that obtained earlier crystals same conditions. satisfactory explained within model cascade Auger transitions, developed for crystalline ma...

In this paper, differences of infrared spectra hydrate formation inhibitors thermodynamic and kinetic action types were investigated. The method was proposed for determining the type a inhibitor by its spectrum. relevance is due to expressiveness in comparison with testing laboratory tests. It use Fourier transform spectrometry. allows us obtain data on molecular intermolecular interactions sub...