Levels of organochlorine compounds (chlorobiphenyls and organochlorine pesticides) were measured in the blubber of 12 marine mammal species collected from strandings around the Scottish and Irish coast. Included are the first contaminant data to be reported in the blubber of the Sowerbys beaked whale (Mesoploden bidens). Twenty CBs were measured, including the toxic non-ortho substituted congen...

BACKGROUND Ambient levels of pesticides ("pesticide drift") are detectable at residences near agricultural field sites. OBJECTIVE Our goal was to evaluate the hypothesis that maternal residence near agricultural pesticide applications during key periods of gestation could be associated with the development of autism spectrum disorders (ASD) in children. METHODS We identified 465 children wi...

Persistent organic pollutants are a concern for species occupying high trophic levels since they can cause immunosuppression and impair reproduction. Mass mortalities due to canine distemper virus (CDV) occurred in Caspian seals (Pusa caspica), in spring of 1997, 2000 and 2001, but the potential role of organochlorine exposure in these epizootics remains undetermined. Here we integrate Caspian ...

BACKGROUND The prevalence of diabetes is higher among Mexican Americans than among non-Hispanic whites. Higher serum levels of organochlorine pesticides in Mexican Americans have been reported. Few studies have explored the association between pesticide exposure and diabetes. OBJECTIVES We set out to examine the association between self-reported diabetes and serum concentrations of organochlo...

The human diet contains industrial-derived, endocrine-active chemicals and higher levels of naturally occurring compounds that modulate multiple endocrine pathways. Hazard and risk assessment of these mixtures is complicated by noadditive interactions between different endocrine-mediated responses. This study focused on estrogenic chemicals in the diet and compared the relative potencies or est...

In this nested case-control study we examined the relationship between non-Hodgkin's lymphoma (NHL) and organochlorine pesticide exposure. We used a data set originally collected between 1969 and 1983 in the U.S. Environmental Protection Agency National Human Adipose Tissue Survey. Adipose samples were randomly collected from cadavers and surgical patients, and levels of organochlorine pesticid...