Drug testing, either on animals or 2D cell cultures, has its limitations due to inaccurate mimicking of human pathophysiology. The liver, as one the key organs that filters and detoxifies blood, is susceptible drug-induced injuries. Integrating 3D bioprinting with microfluidic chips fabricate organ-on-chip platforms for liver cultures continuous perfusion can offer a more physiologically releva...

Plant organs are generated from meristems throughout development. Patterning and elaboration of organ primordia occur as a result of organized cell division and expansion, processes that are likely to be controlled, in part, by meristem-derived signals. Communication between the meristem and lateral organs is crucial for meristem maintenance and organ patterning, and organ boundaries are though...

PURPOSE We compared sexual function in women with pelvic organ prolapse to that in women without prolapse. MATERIALS AND METHODS We collected sexual function data using a standardized, validated, condition specific questionnaire. The study group consisted of 30 women with pelvic organ prolapse and it was compared with 30 unmatched controls without evidence of prolapse. RESULTS The 2 groups ...

Systemic immunoglobulin light chain (LC) amyloidosis (AL) is a potentially fatal disease caused by immunoglobulin LC produced by clonal plasma cells. These LC form both toxic oligomers and amyloid deposits disrupting vital organ function. Despite reduction of LC by chemotherapy, the restoration of organ function is highly variable and often incomplete. Organ damage remains the major source of m...

introduction: the purpose of this study was to compare estimation of radiation absorbed doses to patients following bone scans with technetium-99m-labeled methylene diphosphonate (mdp) with the estimates given in mirdose software. methods: in this study, each patient was injected 25 mci of 99m tc-mdp. whole-body images from thirty patients were acquired by gamma camera at 10, 60, 90, 180 minute...

The paratympanic organ (PO) in birds is a specialised sensory organ whose function is still unknown. G. Vitali, who first described the PO from observations of the behaviour of PO-lesioned pigeons, proposed that this organ was needed to maintain normal wing muscle function and called it the 'organ of flight'. This interpretation has since been disputed. To solve this controversy and to test whe...