outpatient department because of anal bleeding. She had been diagnosedwith ulcerative proctitis about 1 year previously and had experienced intermittent anal bleeding during treatment at a local clinic. She had no significant medication history and in particular had not used laxatives or oral iron. The initial colonoscopy revealed numerous variable-sized areas of black pigmentation in the mucos...

Oral mucosa under physiological condition contains a certain degree of chromic variation. Differentiating such physiological variations from pigmented lesions appears challenging without a histopathological confirmation. In several oral lesions, pigmentation is a part of the primary pathology or a secondary change to an existing entity. The pigments involved in both physiological and pathologic...

membrane bilaterally. Fundus examination revealed no pigmentation. Dental, oral mucosal, skin, and nail pigmentation were evident (Figure 1F). The diagnosis of argyrosis was confirmed by conjunctival biopsy. It was possibly due to occupational inhalation of silver. The Scheimpflug image displayed hyperreflectivity corresponding to corneal pigment accumulation areas at the superficial layers (Fi...

MA: melanoacanthoma INTRODUCTION Oral melanoacanthoma (MA), also known as melanoacanthosis, is a benign, acquired pigmentation infrequently observed in the oral cavity. It represents a distinct entity from the cutaneous MA, which is typically seen on the trunk and is considered to be a variant of seborrheic keratosis. When it occurs in the oral cavity, MA presents as a rapidly expanding, solita...

Laugier-Hunziker syndrome is an acquired macular hyperpigmentation of the oral and genital mucosa, often associated with longitudinal melanonychia. We report a case of longitudinal melanonychia on fingernails and toenails, hutchinson's signal and lenticular pigmentation of her lips and oral mucosa. Histopathological analysis is typical and had a broad differential diagnosis. This is a rare and ...

The aim of the study was to show whether there is any influence of food, drink or drug intake on the formation of tooth discoloration. A total of 500 patients aged 15-25 years were examined to take part in the study. Of these, 60 patients were selected and divided into two groups of 30 patients each. Group 1 included patients with black pigmentation on vestibular/oral tooth surfaces. Group 2 in...

To cite: Nestor LA, Flint S, Galvin S. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217545 DESCRIPTION A 62-year-old Caucasian woman was referred to dermatology by oral medicine regarding intra and extraoral hyperpigmentation which had developed gradually over the past year. Her only significant medical history was stage 4 colorectal carcinoma diagnosed 8 y...