Background The oral squamous cell carcinoma (OSCC) is a malignant neoplasm originating from the epithelial lining of the oral cavity, accounting for about 95% of malignant lesions in this region. In Brazil, the oral cavity is the fifth location of the highest incidence of cancer in men and the seventh in women. In 2012, Brazil was estimated at 9,990 new cases of oral cancer in men and 4,180 in ...

Calcifying epithelial odontogenic tumor is a rare odontogenic neoplasm. Its occurrence in the maxillary sinus is very rare. Maxillary tumors tend to be locally aggressive and may rapidly involve the surrounding vital structures.  We report a case of calcifying epithelial odontogenic tumor involving maxillary sinus in a 48 years old female patient with the oral mucosal involvement. The purpose o...

Primary oral malignant melanoma, very rare neoplasm of melanocytic origin, usually presents as a bluish black to tan-brown colored lesion Which is accounting for 0.2 to 8% of all melanomas, 1.6% of all head and neck malignancies, and 0.5% of all oral neoplasia. In general, the prognosis of oral melanoma is poor and worse than that of cutaneous melanoma. Here a case of oral malignant melanoma is...

We describe the palliative therapy for multiple metachronous oral metastases of hepatocellular carcinoma in a 72-year-old patient with emphasis on maintaining oral functions by local debulking procedures in due consideration of the dissemination of the neoplasm to multiple organs. The first oral metastasis was the first evidence of multiple tumor spread after partial hepatectomy. Palliative che...

Tumors that metastasize to the oral cavity, comprising only about 1% of all oral malignant neoplasms, rarely affect oral soft tissues. The aim of the present case series report is to retrospective study five patients with metastatic tumors to oral soft tissues, retrieved from an institution in southern Taiwan. The age, gender, sites and histological types of the primary tumor, sites of the oral...

Leiomyoma is a rare benign neoplasm deriving from smooth muscle. Vascular leiomyoma is its most common subtype in the oral cavity. It may appear at any age with the greatest incidence in the 4th and 5th decade of life. The common manifestation is a slow-growing, asymptomatic, submucousal mass. The diagnosis is only through microscopic examination requiring special staining...

Abstract A basal cell ameloblastoma is an uncommon benign neoplasm and has a similar histological appearance to carcinoma of the skin. This clinical case report will discuss originating in maxilla baseloid variant. The objective highlight possibility misdiagnosis from this challenging case. 34-year-old male was referred maxillofacial department with recurrent nasal regurgitation following denta...

Oral malignancy is rare in chimpanzees. A 34-year-old female chimpanzee (Pan troglodytes) at Kumamoto Sanctuary, Japan, had developed it. Treatment is technically difficult for chimpanzees while malignant neoplasm is seemingly rising in captive populations. Widespread expert discussion, guidelines for treatment, especially for great apes in terminal stages is urgently needed.

A small subset of cells within a malignant neoplasm, named cancer stem cells (CSCs) or tumour initiating cells, are thought to be capable of initiating the neoplasm itself, and of driving its growth and recurrence after treatment. It is unclear whether CSCs can be identified and experimentally induced within oral squamous cell carcinoma (OSCC), although this has been reported for a number of ot...

Solitary fibrous tumours are spindle-cell neoplasms that usually occur in the pleura and peritoneum, and rarely involve the oral mucosa. We report a 30-year-old man with a large solitary fibrous tumour on the buccal mucosa that resembled a salivary gland neoplasm. The lesion was excised and has not recurred.