BACKGROUND Behçet's disease (BD), first described in 1937 as a triadic complex of symptoms (oral aphthae, genital ulcers, and hypopyon uveitis), is a chronic, relapsing, multisystemic idiopathic inflammatory disease. OBJECTIVE The objective of this study was to investigate the usability of messenger RNA (mRNA) expression of cytokine genes for following up patients with BD and also assess poly...

Behçet's disease (BD) is a chronic relapsing disease involving multiple organ systems. BD is characterized clinically by oral and genital aphthae, cutaneous lesions, and ophthalmological, neurological, and/or gastrointestinal manifestations. It is widely recognized that the presence of intestinal lesions may be a poor prognostic factor in intestinal BD, increasing the risk of surgery and decrea...

Objectives: This study aims to investigate the possible relationship between smoking and otorhinolaryngological symptoms in smokers, nonsmokers and ex-smokers. Patients and Methods: Between March 01st, 2014 and March 31st, 2014, a total of 1,840 patients (823 males, 1,017 females) over 25 years of age who were admitted to the ear nose, and throat (ENT) outpatient clinic were included in the stu...

BACKGROUND/AIM In this study, we aimed to assess the clinical and immunological findings of our patients with common variable immunodeficiency (CVID). MATERIALS AND METHODS We analyzed the records of 31 adult patients with CVID (12 females, 19 males). The patients were classified into clinical and immunophenotypic subgroups for statistical comparisons. RESULTS Our patients had some clinical...

Dear editor, Addition of all-transretinoic acid (ATRA) to antracyclines has been a turning point in the treatment of acute promyelocytic leukemia raising the worldwide complete remission r than 80%. However, a few new side effects have emerged.[1] Among side effects, d syndrome (DS), formerly known as retinoic acid syndrome, is the main life complication of therapy with differentiating agents [...

SARAL, Y., COSKUN, B.K., OZTURK, P., KARATAS, F. and AYAR, A. Assessment of Salivary and Serum Antioxidant Vitamins and Lipid Peroxidation in Patients with Recurrent Aphthous Ulceration. Tohoku J. Exp. Med., 2005, 206 (4), 305-312 ── Recurrent aphthous ulceration (RAU) is a common oral mucosal disorder characterized by recurrent, painful oral aphthae. Although the exact cause of RAU is not know...

362 A 39-year-old nurse was referred for evaluation of bone lesions. Seven months earlier she had undergone a hysterectomy because of severe vaginal discharge and urge incontinence. Two months after the operation, she noticed pain in the mid left clavicula. There was no trauma, fever, redness or swelling. In the same period she developed red, itchy and scaling skin lesions of both hands, left f...

B ehçet’s syndrome is a chronic, relapsing, multisystemic, inflammatory disorder. The diagnosis of Behçet’s syndrome is based on clinical criteria and no pathognomonic laboratory findings exist. A diagnosis is made by the presence of recurrent oral ulceration, the hallmark of this disease, plus any two of the following: recurrent genital ulcerations, ocular lesions (anterior or posterior uveiti...

Background The main manifestation of Behçet’s disease is oral aphthae. Treatment consists topical corticosteroids and colchicine in recurrent cases. Drugs such as azathioprine, thalidomide, interferon-alpha, tumour necrosis factor-alpha inhibitors or apremilast should be considered selected cases [1] . A phase 3, double-blind, placebo-controlled RELIEF study suggests that an effective agent for...