PURPOSE To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. DESIGN Population-based study. METHODS In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50-93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with...

PURPOSE To examine the influence of body height, body weight, and body mass index (BMI) on optic disc parameters in a population-based study. METHODS The Singapore Malay Eye Study examined 3280 persons of Malay ethnicity, aged 40 to 80 years, of whom 2329 (71.0%) had reliable retinal scanning confocal laser tomography images for analyses. Intraocular pressure (IOP) was ascertained by Goldmann...

PURPOSE To determine the frequency of optic disc hemorrhages in a rural Indian population. METHODS The population-based Central Indian Eye and Medical Study included 4711 subjects. Mean age was 48.5±12.9 years (range: 30-100 years). Color optic disc photographs were examined. RESULTS Optic disc photographs were available for 4570 (97.0%) subjects. Prevalence of disc hemorrhages was 17/8869 ...

BACKGROUND Optic disc drusen, which are calcified deposits that form anterior to the lamina cribrosa in the optic nerve, may mimic papilledema. CASE REPORT We report herein three cases referred to us with suspicion of disc swelling and papilledema. Following ophthalmologic evaluation with B-scan ultrasound, red-free fundus photography, and computed tomography, the diagnosis of papilledema was...

purpose: to present a case of herpes zoster ophthalmicus (hzo) with consequent posterior ischemic optic neuropathy (pion). case report: a 58-year-old woman with a history of hzo in her right eye which was under treatment presented with loss of vision to no light perception. on examination, positive relative afferent pupillary defect was detected; however the optic disc was normal on ophthalmosc...

OBJECTIVE To assess the relationship between in vivo measurements of optic disc topography and histomorphometric measurements of optic nerve fiber number in glaucoma. METHODS Both eyes of 10 monkeys (Macaca fascicularis) with laser-induced glaucoma in the right eye were studied. Optic disc topography was measured in vivo with a confocal scanning laser ophthalmoscope. Histomorphometry was perf...

This paper describes two complementary methods for computer analysis of the optic disc in glaucoma. The objective of both techniques is to detect and monitor changes in the optic disc through the use of digital image processing techniques that allow user intervention. In the first method, optic disc photographs from successive years are digitized, scaled and registered (aligned) with each other...

PURPOSE The parapapillary gamma zone has been defined as the parapapillary region without Bruch's membrane. We examined which morphologic parameters are associated with the presence and size of the parapapillary gamma zone. METHODS Using fundus photographs and spectral-domain optical coherence tomographic images of the optic nerve head in the population-based Beijing Eye Study, we determined ...

PURPOSE To investigate the effect of systemic nitric oxide synthase (NOS) inhibition on optic disc oxygen partial pressure (PO(2)) in normoxia and hypercapnia. METHODS Intervascular optic disc PO(2) was measured in 12 anesthetized minipigs by using oxygen-sensitive microelectrodes placed <50 microm from the optic disc. PO(2) was measured continuously during 10 minutes under normoxia, hyperoxi...

AIMS Progressive loss of neuroretinal rim tissue is known to occur early in glaucoma and measurement of the neuroretinal rim area is possible by magnification corrected analysis of optic disc photographs (planimetry). This study was performed to determine whether the facility to distinguish between glaucomatous and normal optic discs could be improved upon by: (a) taking into account the known ...