Congenital abnormalities of the optic disc are not so rare. The etiology for the most of them is unknown. Visual acuity of affected eye may be minimally or severely affected, depending on the extent of lesion. All of these conditions can be unilateral or bilateral. Children who have unilateral optic disc abnormalities generally present during the preschool years with sensory esotropia. Visual a...

Automated fundus image analysis plays an important role in the computer aided diagnosis of ophthalmologic disorders. A lot of eye disorders, as well as cardiovascular disorders, are known to be related with retinal vasculature changes. Many studies has been done to explore these relationships. However, most of the studies are based on limited data obtained using manual or semi-automated methods...

Glaucoma detection system analyses the retinal images. This system gives vital information about presence of Glaucoma, the second largest cause of blindness. Usually the Glaucoma patients have large Cup-to-Disc ratio (CDR), inspection of CDR of Optic Disc is crucial of any Glaucoma detection system. Therefore accurate segmentation Optic Disc (OD) and Cup are critical in the formulation of CDR. ...

AIMS/BACKGROUND It has been reported that the number of optic nerve fibres decrease with age, and the cup/disc (C/D) ratio increases as the optic disc size increases. Consequently, the normal value of the optic disc variables measured by an optic disc analyser may change according to the optic disc size or age. The effect of individual variations in optic disc size or age on interpretation of o...

Optic disc pit and optic nerve coloboma are examples of congenital optic disc abnormalities. Although optic nerve coloboma can be inherited in an autosomal dominant fashion, no conclusive link has been found in the case of optic disc pit as an autosomal dominant disease. We describe two cases: a daughter with an optic disc pit complicated by maculopathy and her mother with a congenitally abnorm...

For a computer aided detection system of retinal lesions, optic disc (OD) detection is the first and the most importance. Since the OD is once detected then other clinical importance regions such as fovea or macula can easily be determined, and the OD shape is often used to evaluate abnormal retinal features for diagnosis of abnormalities such as hypertensive retinopathy. In this paper, an appr...

purpose : to present a patient with radiation chiasma neuropathy, secondary to radiotherapy of paranasal sinus lymphoma who was referred for evaluation of gradual decrease of vision in both eyes case report : the patient was a 38-year-old male, with history of right maxillary sinus lymphoma, who underwent surgery, chemotherapy and radiation therapy. one year after radiotherapy, he noticed gradu...

PURPOSE To compare the earliest detection of progression in visual fields and monoscopic optic disc photographs at different stages of manifest glaucoma. METHODS This study evaluated 306 eyes in 249 patients with manifest open-angle glaucoma included in the Early Manifest Glaucoma Trial (EMGT). All patients in the trial were followed up regularly by standard automated perimetry and monoscopic...

PURPOSE The defining feature of glaucoma is excavation of the optic nerve head; however, the mechanism of this loss of tissue is not well understood. We recently discovered a copy number variation upstream of matrix metalloproteinase 19 (MMP19) in a large, autosomal dominant pedigree with a congenital malformation of the optic disc called cavitary optic disc anomaly (CODA). Patients with CODA h...

Diabetic Retinopathy (DR) is one of the main causes of vision loss in the world among patients suffering from diabetes. DR is a chronic eye disease, which can be controlled by regular checkup & treatment. If left untreated, loss of vision occurs gradually and become blind. The detection and diagnosis of DR is important. DR is characterized by its features like, micro aneurysms (MAs), hemorrhage...