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we evaluated the ability of spectral-domain optic coherence tomography (sd-oct) to differentiate large physiological optic disc cupping (lpc) from glaucomatous cupping in eyes with intraocular pressure (iop) within the normal range.â  we prospectively enrolled patients with glaucoma or presumed lpc. participants â had optic discs with confirmed or suspected glaucomatous damage (defined as a ver...

Coriandrum sativum (coriander) has been documented as a traditional treatment of diabetes. On the base of this belief and as the studies about whether coriander reduces hyperglycemia in diabetic mice is little known are lacking, we decided to evaluate the effect of Aqueous Extract seed of Coriander on optic nerve in Balb/c Diabetic Mouse. In the present study, the beta cells of pancreas of 16 b...

to improve visual disturbance, optic nerve decompression can be performed via transcranial or tran-sphenoidal approaches. although the surgical exposure in transcranial approach is favourable, yet the optic nerve's presence in the field may make it vulnerable to damage. of fighty patients with different types of pituitary adenomas, 35 cases with medium-sized (1-3 cm) tumors have been studi...

purpose: to evaluate the role of transvitreal optic neurotomy (ton) in the management of non-arteritic anterior ischemic optic neurotomy (naion). methods: sixteen eyes of 16 patients with recent onset naion (less than six weeks duration) were included in this single-masked randomized controlled trial. the patients were randomized to ton (8 eyes) versus observation alone (8 eyes). pre- and posto...

Background: Multiple sclerosis and other demyelinating processes are sometimes difficult to differentiate from the neurological involvement in autoimmune diseases. Distinguishing multiple sclerosis from other lesions due to autoimmune diseases is crucial to avoid unsuitable or delayed treatments. Methods: Charts of 6 patients diagnosed with mimicking multiple sclerosis between 1996 and 2014 we...

OBJECTIVE To determine the prevalence of tilted and torted optic discs and associated risk factors among Chinese adults in Singapore. METHODS As part of a population-based survey, optic disc stereophotographs of both eyes were obtained, and left eyes were analyzed using imaging software. A tilted optic disc was defined as an index of tilt (ratio of minimum to maximum optic disc diameter) less...

Optic disc pit and optic nerve coloboma are examples of congenital optic disc abnormalities. Although optic nerve coloboma can be inherited in an autosomal dominant fashion, no conclusive link has been found in the case of optic disc pit as an autosomal dominant disease. We describe two cases: a daughter with an optic disc pit complicated by maculopathy and her mother with a congenitally abnorm...

The term optic neuritis denotes primary inflammation of the optic nerve. When the clinical history and examination suggest optic neuritis and the optic disk appears normal, the term retrobulbar optic neuritis is used. Critical elements in establishing the diagnosis are a detailed history and an accurate examination. For this reason, the ophthalmologist must be familiar with the clinical profile...