AIM To study survival in isolated coronary artery bypass graft (CABG) patients and to evaluate the impact of preoperative chronic opium consumption on long-term outcome. METHODS Cohort of 566 isolated CABG patients as Tehran Heart Center cardiac output measurement was conducted. Daily evaluation until discharge as well as 4- and 12-mo and 6.5-year follow-up information for survival status wer...

The effect of the endogenous opioid system as analgesics was not identified until the early 1970’s [1]. Since the 3rd century BC, however, it has been known that opium as the main compound of opiates, harvested from the juice of the opium poppy was of use in managing pain, as well being addictive [1,2]. The introduction in 1680 of Sydenham’s Laudanum, a mixture of opium with sherry wine and her...

The effect of opium addiction on the appearance of different types of arrhythmias after acute myocardial infarction (AMI) has been assessed in few studies. This study is aimed to determine the effect of opium on post-MI arrhythmia and also to address the differences in the appearance of different types of arrhythmias after AMI between opium addicted and non-addicted patients. In this comparativ...

INTRODUCTION Laryngeal cancer is the second most common cancer involving the respiratory tract, second only to lung cancer. Previous studies have shown opium dependency to be a possible risk factor for laryngeal cancer. Opium consumption is a major problem in some parts of the world. The aim of this study was to investigate the effect of opium consumption on the pattern of involvement in laryng...

BACKGROUND Recent studies have suggested that opium use may increase mortality from cancer and cardiovascular diseases. However, no comprehensive study of opium use and mortality from respiratory diseases has been published. We aimed to study the association between opium use and mortality from respiratory disease using prospectively collected data. METHODS We used data from the Golestan Coho...

as aromatic stimulants or purgatives, it is probable that some substitutes might be procured from our Indian Materia Medica ; and I therefore forward a list of the component parts shewing how the Tincture could be made out of ingredients obtainable in our Bazaars, with the exception, I must confess, of the two principal articles in it, viz., the quinine and the spirit. But of these the latter i...

BACKGROUND Lead (Pb) poisoning among people using opium has been an increasing problem in Iran. The present study highlights the clinical effects of lead toxicity associated with opium use in Iran, Kerman province. METHODS Between January 2016 and June 2016, patients with signs and symptoms of Pb poisoning were questioned to assess whether they had a history of opium dependency. In total, 249...

Because of its geographic proximity to the major drug production centres, there is easy access to narcotic drugs in the Islamic Republic of Iran despite efforts by governmental and nongovernmental organizations. Using a structured questionnaire as a basis for conversation, local health workers interviewed 310 residents of a rural area in Babol province about opium use. The self-reported rate of...

BACKGROUND Opium dependency is an important health problem in Iran. Several studies show that most opium dependent patients have concomitant psychiatric disorders. The aim of this study was evaluation of psychiatric disorders in opium dependency in comparison with heroin dependency. METHODS This is a descriptive study on 192 male opium dependent patients who were admitted in dual- diagnosis w...

A survey on opium use was earned out in Tinsukia district of upper Assam to assess the present prevalence and pattern of opium abuse and compared with earlier findings of the year 1981 (Baruah et al., 1995). A total of 75 addicts could be detected during the survey and 61 were interviewed using structured questionnaire. The results indicate significant decline in prevalence in opium use over th...