Background: Evidences show that parental morphine addiction impairs CNS development, learning and memory in offsprings. Since long term potentiation (LTP) is a cellular mechanism of learning and memory, in this study the effect of parental morphine addiction on LTP induction in dentate gyrus by high frequency stimulation of perforant path was assessed. Materials and methods: In this experiment...

abstract background and objective: nas is a combination of signs and symptoms that due to physical and mental dependency, develops in neonates born from drug addicted mothers. the onset of nas varies in accordance with the type, amount, frequency and duration of substance used. because of diverse and unclear pattern of substance abuse in iranian addicted pregnant mothers in comparison with west...

By attempting to quit and seeking help from others, you've already taken a remarkable first step in the direction of change. For those who may be unfamiliar, methadone is a synthetic opioid drug that is commonly used to treat narcotic or opiate addiction (such as heroin). Regardless of whether you started taking methadone to treat a drug addiction, pain, or for recreational purposes, it can be ...

example is inflammation: perhaps the simplest form of pathology. It has well defined characteristics which, for many of the old continent, were described in latin: rubor, tumor, calor, dolor, and functio lesa. When these characteristics are present, the pathology/disease can be diagnosed. If it occurs in the lung it will indicate pneumonia, in the kidney nephritis etc. Likewise, a brain chronic...

BACKGROUND Although the triggering role of both opium use and elevated plasma homocysteine level for progressing atherosclerosis and, therefore, appearing coronary heart disease has been clearly determined, no study are available with respect to the relation between these to risk profiles. In the present study and for the first time, we hypothesized that the opium addiction can be potentially c...

Temperate people were naturally contrasted with the intemperate. Thus, there was “intemperance as to strong liquours [13]” as well as “given to the intemperate use of malt and spirituous liquours [14].” There was also the generalized description concerning “an intemperate man [15].” Intemperance was described in a woman who “had been for many years a notorious dram-drinker [16].” Scarpa [17] no...

Laryngeal cancer is a disease of old age and the most common age of presentation is 6Th. 7Th decade of life. This disease is more common in men, but male to female ratio has been decreased from 15:1 to 4:1 during the last forty years. The most common risk factors are cigarette smoking and alcohol consumption. This cross – sectional study carried out to determine the age of laryngeal cancer from...