OBJECTIVES To describe hospital inpatient, emergency department (ED) and outpatient department (OPD) activity for patients in the year following their first emergency admission for heart failure (HF). To assess the proportion receiving specialist assessment within 2 weeks of hospital discharge, as now recommended by guidelines. DESIGN Observational study of national administrative data. SET...

Peritoneal inflammation and fibrosis are responses to the uremic milieu and exposure to hyperosmolar dialysis fluids in patients on peritoneal dialysis. Cells respond to high osmolarity via the transcription factor nuclear factor of activated T cells (NFAT5). In the present study, the response of human peritoneal fibroblasts to glucose was analyzed in vitro. Expression levels of NFAT5 and chemo...

We present a ternary blend-based bulk heterojunction ITO/PEDOT:PSS/PFO-DBT: MEH-PPV:PC71BM/LiF/Al photodetector. Enhanced optical absorption range of the active film has been achieved by blending two donor components viz. poly[2,7-(9,9-di-octyl-fluorene)-alt-4,7-bis(thiophen-2-yl)benzo-2,1,3-thiadiazole] (PFO-DBT) and poly(2-methoxy-5(2'-ethylhexyloxy) phenylenevinylene (MEH-PPV) along with an ...

PURPOSE To compare total ocular aberrations and corneal aberrations identified with four different aberrometers and to determine the repeatability and interobserver variability. METHODS In this prospective comparative study, 23 healthy subjects underwent bilateral examination with four aberrometers: the Irx3 (Hartmann-Shack; Imagine Eyes, Orsay, France), Keratron (Hartmann-Shack; Optikon, Rom...

We have carried out an analysis of whether blood IgG antibodies can protect humans from oxidative stress by oxidizing different harmful compounds. A somewhat unexpected result was obtained. We show here for the first time that healthy human sera IgGs with the peroxidase (in the presence H2O2) efficiently oxidize different compounds: 3,3'-diaminobenzidine (1; DAB), 2,2'-azino-bis(3-ethylbenzothi...

The importance of open data and the benefits it can offer have received recognition on the international stage with the signing of the G8 Open Data Charter in June 2013. The charter has an early focus on 14 high value areas, including transport and education, where governments have greater influence. In the UK, we have seen the funding of the Open Data Institute (ODI) with a remit to support sm...