OBJECTIVE To evaluate the maturation and post-thaw survival rates of immature oocytes to determine whether in vitro maturation (IVM) should be attempted prior to or after cryopreservation. DESIGN Nonrandomized observational study. SETTING Private academic and clinical reproductive center. PATIENT(S) Patients (n = 71) who donated immature unusable oocytes after vaginal oocyte retrieval (VO...

Abstract Study question What is the fate of cryopreserved oocytes? Summary answer Very few people return to use their oocytes in assisted reproduction and while some surplus are donated for reproduction, majority discarded. known already The number oocyte cryopreservation cycles performed around world dramatically outpaces who reproduction. This imbalance leading rapid accumulation cryostorage....

BACKGROUND Healthcare costs are increased by the adoption of novel technologies before solid evidence on efficacy and risks. Oocyte cryopreservation for preserving fertility raises special ethical challenges. We compared opinions of professionals for assisted reproductive technology (ART), bioethicists, medical students and the general population toward the questions: do you support access to o...

•Prophylactic oophorectomy can prevent small cell carcinoma of the ovary, hypercalcemic type in carriers of germline SMARCA4 mutations.•Unaffected SMARCA4 mutation carriers who desire children may be best served by oocyte cryopreservation prior to prophylactic oophorectomy.

The physiological trigger for meiotic resumption in the human oocyte is the surge of luteinizing hormone, but it can also occur spontaneously if oocytes are released from antral follicles and cultured in vitro. The development of novel techniques for the culture of murine oocytes has raised the possibility of growing human oocytes to maturity in vitro. Such a system could open the door to a num...

The method of vitrification has been widely used for cryopreservation. However, the effectiveness of this method for mammalian oocytes could be improved by optimizing each step of the process. In the present study, we tested the effects of varying several key parameters to determine the most effective protocol for mouse oocyte vitrification. We found that cryoprotectant containing ethylene glyc...

Oocyte intracellular lipids are mainly stored in lipid droplets (LD) providing energy for proper growth and development. Lipids are also important signalling molecules involved in the regulatory mechanisms of maturation and hence in oocyte competence acquisition. Recent studies show that LD are highly dynamic organelles. They change their shape, volume, and location within the ooplasm as well a...

Aim: The objective of this descriptive study was to evaluate the attitudes towards oocyte cryopreservation among Turkish nursing and midwifery students. Method: sample consisted 342 female students in departments two universities Istanbul. A questionnaire about their socio-demographic characteristics, knowledge views applied online volunteer Results: average age participants 20.96±1.8. wanted h...

Background Fertility preservation for female cancer patients prior to cancer therapy has emerged as an essential component of comprehensive patient care. In the US, approximately 6% of women diagnosed with invasive cancer between 2007 and 2011 that were under 45 years old. The incidence of cancers in reproductive age women signifies a need for fertility preservation options and this need is inc...