(-)-Ambrox is recognised as the prototype of all ambergris odorants. Widely used in perfumery, (-)-Ambrox is an important ingredient due to its unique scent and excellent fixative function. An environmentally friendly and practical preparation of (-)-Ambrox is still unavailable at present although a lot of attention has been paid to this hot research topic for many years. A one-pot synthesis of...

a highly efficient procedure for the preparation of n,n'-alkylidenebisamides in the presence of bf3.sio2 as a catalyst is described. n,n'-alkylidenebisamides have been prepared via one-pot three-component condensation reaction of various aldehydes and amides. all of the reactions proceeded in high yields and in moderately short reaction times.

An efficient green route for the preparation of naphthoxazinones, applying a three-component one-pot condensation reaction of 2-naphthol, aromatic aldehyde and urea in the presence of nano silica supported ferric chloride under solvent-free conditions has been developed. The present procedure offers several advantages such as short reaction time, simple workup, recovery and reusability of the c...

An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.

An efficient one-pot condensation for the synthesis of 1,8-dioxo-octahydroxanthene is  achieved through a condensation of aryl aldehydes and 5,5-dimethyl-1,3-cyclohexandione in the presence of  NBS. This method enjoys several advantages such as low cost, simple work up procedure and safe reaction condition. In addition, water was chosen as a green solvent.