OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...

The first issue of the World Journal of Critical Care Medicine (WJCCM), whose preparatory work was initiated on December 16, 2010, will be published on February 4, 2012. The WJCCM Editorial Board has now been established and consists of 105 distinguished experts from 27 countries. Our purpose of launching the WJCCM is to publish peer-reviewed, high-quality articles via an open-access online pub...

This paper investigates the design and application of write-once memory (WOM) codes for flash memory storage. Using ideas from Merkx [1], we present a construction of WOM codes based on finite Euclidean geometries over F2. This construction yields WOM codes with new parameters and provides insight into the criterion that incidence structures should satisfy to give rise to good codes. We also an...

Much of the public lacks a proper understanding of Darwinian evolution, a problem that can be addressed with new learning and teaching approaches to be implemented both inside the classroom and in less formal settings. Few analogies have been as successful in communicating the basics of molecular evolution as John Maynard Smith's protein space analogy (1970), in which he compared protein evolut...

A celebrated contribution of Bellantoni and Cook was a function algebra to capture FPTIME. This algebra uses recursion on notation. Later, Oitavem showed that including primitive recursion, an algebra is obtained which captures FPSPACE. The main results of this paper concern variants of the latter algebra. First, we show that iteration can replace primitive recursion. Then, we consider the resu...

In a world where images of picture-perfect celebrities are plastered everywhere, it can be alarmingly easy to fall into a movie star crush. But it sounds like you?re worried that your wife?s crush may be getting out of hand ? or, at the very least, is seriously straining your marriage. It?s not unusual to feel hurt, jealous, or confused if your partner is pining over some hot-shot with (movie) ...

In this ongoing work we perform the first systematic investigation of cross-platform (X-platform) malware. As a first step, this paper presents an exploration into existing X-platform malware families and X-platform vulnerabilities used to distribute them. Our exploration shows that Xplatform malware uses a wealth of methods to achieve portability. It also shows that exploits for X-platform vul...

José Clavijo y Fajardo’s satirical allegory, El tribunal de las damas, certainly fulfils the great Roman satirist Horace’s utili dulci dictum, so prized by Spain’s neoclassicists, on the importance of literature’s being both entertaining and instructive. Its witty representation of the age-old debate about the balance of power between the sexes, in the form of a court-room battle over the intro...

These notes are intended to merely augment and not completely reproduce the recorded lectures. I think it's can be a little tough to see what he's writing, so I think this will be helpful. Professor Benedetto gives significant informative exposition during his lectures (which I appreciate). I have to apologize, but I have largely left this out. This is not out of disrespect, but it's hard to do...