Brain nuclei are spatially organized collections of neurons that share functional properties. Despite being central to vertebrate brain circuitry, little is known about how nuclei are generated during development. We have chosen the chick midbrain oculomotor complex (OMC) as a model with which to study the developmental mechanisms of nucleogenesis. The chick OMC comprises two distinct cell grou...

The aim of this study was to clarify the synergistic effects of dual inhibition of the PI3K/mTOR and MAPK pathways in ovarian mucinous carcinoma (OMC) cells, using fluorescence resonance energy transfer (FRET) imaging. We exposed 6 OMC cell lines to a PI3K/mTOR inhibitor (voxtalisib, SAR245409) and/or a MEK inhibitor (pimasertib), and evaluated synergistic effects using the Chou-Talalay method....

SUMMARY Optical wireless communications is a research topic of extreme interest since it offers high data rate (Gbps data rate), security, and RF interference immunity. However, optical wireless communications places severe restrictions on the communications paths; they must be direct beam connections. To increase the number of users and link robustness, optical wireless communications must be ...

Soil stabilization is the alteration of physicomechanical properties soils to meet specific engineering requirements problematic soils. Laboratory examination well recognized as appropriate for examining stabilized soils; however, they are labor-intensive, time-consuming, and expensive. In this work, four artificial intelligence based models (OMC-EM, MDD-EM, UCS-EM+, UCS-EM−) predict optimum mo...

ordered mesoporous carbon cmk-3 (omc) have been synthesized using mesoporous sba-15 silica as template and modified with cobalt carbonate. morphologies and surface texturing of materials werecharacterized by x-ray diffraction (xrd), scanning electron microscopy (sem) and n2 adsorption-desorptionisotherms. the cobalt modified ordered mesoporous carbon were found to have a surface area of 490.06m...

El sistema de solución diferencias la Organización Mundial del Comercio (OMC) está en crisis desde que su Órgano Apelación dejó funcionar diciembre 2019. Como consecuencia, el Solución Diferencias OMC no puede adoptar informe un grupo especial si una parte diferencia notifica intención apelar. En ese contexto, presente artículo analiza qué factores pueden influir decisión las partes reclamantes...

INTRODUCTION Classic teaching suggests that disease in the osteomeatal complex (OMC) plays a pivotal role in the establishment of chronic rhinosinusitis (CRS). We sought to test this hypothesis. METHODS Retrospective review of 106 consecutive patients enrolled prospectively into an allergy/sinus centre database, meeting Task Force criteria for CRS. Inflammatory disease was scored radiological...

Ab initio density functional simulations have been performed to study the adsorption of propene on partially oxidized silver surfaces and its interaction with surface oxygen. Two different adsorption conformations for propene are studied, with the molecule either intact or forming an Ag-C3H6-O oxymetallacycle (OMC) intermediate. Then, pathways for propene oxide, acrolein and propanone formation...

Jacobian matrices are used in a wide range of applications from solving the original DAEs to sensitivity analysis. Using Automatic Differentiation the necessary partial derivatives can be provided efficiently within a Modelica-Tool. This paper describes the corresponding implementation work within the OpenModelica Compiler (OMC) to create a symbolic derivative module. This new OMC-feature gener...

WTO dispute settlement continues to be the subject of extensive scrutiny by both trade practitioners and academics. Not surprisingly, most of this analysis is legal in nature, touching upon the various arguments that have been put forward by parties to disputes and the legal foundations upon which these disputes are adjudicated. While legal and procedural issues remain the domain of trade lawye...