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BACKGROUND AND OBJECTIVE Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1, GSTM1and GSTT1, that code for drug-metabolizing enzymes. This study evaluated whether the polymorphisms in these enzymes were associated with an in...
Rahman, l.r.c p. and lf.p s. (Glas.), Civil Surgeon, Burma. This Manual 1ms been compiled by Dr. Rahman to explain the methods of vaccination and its superiority to the dangerous practice of inoculation against small-pox. We entirely agree with him that a systematic training is necessary in the method of vaccination. The first chapter deala with the mortality from small-pox, its infectivity, it...
BACKGROUND Surveys have demonstrated a lack of physician awareness of intra-abdominal hypertension and abdominal compartment syndrome (IAH/ACS) and wide variations in management of these conditions, with many intensive care units (ICUs) reporting that they do not measure intra-abdominal pressure (IAP). We sought to determine the association between publication of the 2006/2007 World Society of ...
BACKGROUND Increased potassium intake has been shown to lower blood pressure (BP) even in the presence of high sodium consumption however the role of dietary potassium on vascular function has received less attention. The aim of this study was to evaluate the relationship between habitual intake of sodium (Na) and potassium (K) and measures of arterial stiffness and wave reflection. METHODS T...
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